Announcements Trials
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Phase

Phase 3 2Phase 2 1Phase 1/2 1

Status

Completed 25Active not recruiting 5Terminated 4Recruiting 4Unknown 3Not yet recruiting 2Withdrawn 1

Sponsor Class

OTHER 2NIH 1NETWORK 1

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Small Cell Lung Carcinoma 9Ovarian Neoplasms 8Neuroblastoma 4Retinoblastoma 3Fallopian Tube Neoplasms 3Sarcoma, Ewing 2Lung Neoplasms 2Ganglioneuroblastoma 2Carcinoma, Ovarian Epithelial 2Brain Neoplasms 2Wilms Tumor 1Uterine Cervical Neoplasms 1Recurrence 1Pleuropulmonary blastoma 1Peritoneal Neoplasms 1Pediatric Brain Tumor 1Osteosarcoma 1Neoplasms 1Neoplasm Metastasis 1Medulloblastoma 1Lymphoma, Follicular 1Leukemia, Myeloid, Acute 1Glioma 1Extensive Stage Small Cell Lung Cancer (ES-SCLC) 1Endometrial Neoplasms 1Cholangiocarcinoma 1Central Nervous System Neoplasms 1Carcinoma, Non-Small-Cell Lung 1

Interventions

Temozolomide 16Irinotecan 13Cyclophosphamide 11dinutuximab 9naxitamab 7Vincristine 7Carboplatin 6sargramostim 5Melphalan 5Granulocyte-Macrophage Colony-Stimulating Factor 5Etoposide 5fludarabine 4Topotecan 4Thiotepa 4Eflornithine 4Doxorubicin 4Cisplatin 4etoposide phosphate 3Zoledronic Acid 3Specimen Handling 3Isotretinoin 3Granulocyte Colony-Stimulating Factor 3saponin QA-21V1 2lutetium Lu 177 dotatate 2aldesleukin 2Vorinostat 2Stem Cell Transplantation 2Radiation 2Platinum 2Mesna 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Recruiting × Neuroblastoma × Topotecan × Clear all
NCT06172296 2026-06-03

Dinutuximab With Chemotherapy, Surgery and Stem Cell Transplantation for the Treatment of Children With Newly Diagnosed High Risk Neuroblastoma

National Cancer Institute (NCI)

Phase 3 Recruiting
478 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Children's Oncology Group

Phase 3 Recruiting
750 enrolled
CNS

Neuroblastoma, Ganglioneuroblastoma

NCT06528496 2026-02-10

N10: A Study of Reduced Chemotherapy and Monoclonal Antibody (mAb)-Based Therapy in Children With Neuroblastoma

Memorial Sloan Kettering Cancer Center

Phase 2 Recruiting
45 enrolled
CNS

Neuroblastoma

NCT07334301 2026-01-12

BEACON2

University of Birmingham

Phase 1/2 Recruiting
160 enrolled
CNS

Neuroblastoma

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