Announcements Trials
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Phase

Phase 1/2 1Phase 1 1

Status

Terminated 1Completed 1

Sponsor Class

INDUSTRY 2

Study Type

Interventional 2

Sponsor

Cancer Type

Other hematologic neoplasm 2Lymphoid 2CNS 2

Conditions

Leukemia, Myeloid, Acute 311Leukemia, Lymphocytic, Chronic, B-Cell 108Myelodysplastic Syndromes 63Recurrence 55Leukemia 43Neoplasms 42Precursor Cell Lymphoblastic Leukemia-Lymphoma 41Lymphoma, Non-Hodgkin 41Lymphoma, Mantle-Cell 32Multiple Myeloma 28Lymphoma, Large B-Cell, Diffuse 27Leukemia, Myelomonocytic, Chronic 27Lymphoma, Follicular 22Lymphoma 21Hematologic Neoplasms 20Lymphoma, B-Cell, Marginal Zone 18Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 17Leukemia, Biphenotypic, Acute 16Burkitt Lymphoma 16Myeloproliferative Disorders 11Lymphoma, B-Cell 11Leukemia, Myeloid 11Neoplasm, Residual 10Leukemia, Myelogenous, Chronic, BCR-ABL Positive 10Waldenstrom Macroglobulinemia 9Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 7Chromosome 17 deletion 6Leukemia, B-Cell 5Immunoglobulin Light-chain Amyloidosis 5Breast Neoplasms 5

Interventions

Cyclophosphamide 101Etoposide 60Carboplatin 55Vincristine 51Filgrastim 49Topotecan 44Temozolomide 44Melphalan 44Isotretinoin 44Doxorubicin 44Irinotecan 42Cisplatin 353-Iodobenzylguanidine 34Peripheral Blood Stem Cell Transplantation 31dinutuximab 30Granulocyte Colony-Stimulating Factor 30Radiotherapy 29sargramostim 28Granulocyte-Macrophage Colony-Stimulating Factor 25Busulfan 22Magnetic Resonance Spectroscopy 19aldesleukin 18Thiotepa 18fludarabine 17Interleukin-2 17humanized 3F8 anti-GD2 monoclonal antibody 16etoposide phosphate 16naxitamab 15Ifosfamide 15Biopsy 13

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neuroblastoma × venetoclax × Clear all
NCT04029688 2024-12-20

A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

Hoffmann-La Roche

Phase 1/2 Terminated
38 enrolled 34 charts
CNSLymphoidOther hematologic neoplasm

Neuroblastoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03236857 2023-05-22

A Study of the Safety and Pharmacokinetics of Venetoclax in Pediatric and Young Adult Patients With Relapsed or Refractory Malignancies

AbbVie

Phase 1 Completed
143 enrolled
CNSLymphoidOther hematologic neoplasm

Lymphoma, Non-Hodgkin, Neoplasms, Neuroblastoma, Recurrence, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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