Announcements Trials
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Phase

Phase 1/2 1

Status

Terminated 1Completed 1

Sponsor Class

INDUSTRY 1

Study Type

Interventional 1

Sponsor

Cancer Type

Other hematologic neoplasm 1Lymphoid 1CNS 1

Conditions

Leukemia, Myeloid, Acute 41Myelodysplastic Syndromes 13Leukemia, Lymphocytic, Chronic, B-Cell 12Neoplasms 9Leukemia, Myelomonocytic, Chronic 8Leukemia 8Recurrence 7Lymphoma, Non-Hodgkin 7Lymphoma, Large B-Cell, Diffuse 7Lymphoma, Follicular 7Precursor Cell Lymphoblastic Leukemia-Lymphoma 6Lymphoma, Mantle-Cell 5Lymphoma, B-Cell, Marginal Zone 4Hematologic Neoplasms 4Breast Neoplasms 4Neoplasm Metastasis 3Multiple Myeloma 3Lymphoma, B-Cell 3Leukemia, Myeloid 3Myeloproliferative Disorders 2Leukemia, Myelogenous, Chronic, BCR-ABL Positive 2Leukemia, Biphenotypic, Acute 2Blast Crisis 2Thrombocytosis 1Small Cell Lung Carcinoma 1Sarcoma 1Prostatic Neoplasms 1Primary Myelofibrosis 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Pancreatic Neoplasms 1

Interventions

Cyclophosphamide 6Isotretinoin 5thymoglobulin 4fludarabine phosphate 4fludarabine 4aldesleukin 4Topotecan 4Temozolomide 4Melphalan 4Irinotecan 4Etoposide 4ribociclib 3Thiotepa 3Interleukin-2 3Granulocyte Colony-Stimulating Factor 3Filgrastim 3Busulfan 3Bone Marrow Transplantation 3Antilymphocyte Serum 3temsirolimus 2omburtamab I-131 2dinutuximab 2Vincristine 2Tretinoin 2TPI-287 2Stem Cell Transplantation 2Rituximab 2Radiotherapy 2Peripheral Blood Stem Cell Transplantation 2Nivolumab 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Neuroblastoma × venetoclax × Clear all
NCT04029688 2024-12-20

A Study Evaluating the Safety, Tolerability, Pharmacokinetics and Preliminary Activity of Idasanutlin in Combination With Either Chemotherapy or Venetoclax in Treatment of Pediatric and Young Adult Participants With Relapsed/Refractory Acute Leukemias or Solid Tumors

Hoffmann-La Roche

Phase 1/2 Terminated
38 enrolled 34 charts
CNSLymphoidOther hematologic neoplasm

Neuroblastoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

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