Clinical Trials

65 enrolled

Neuroblastoma, Ganglioneuroblastoma

NCT04897321 2026-05-19

B7-H3-Specific Chimeric Antigen Receptor Autologous T-Cell Therapy for Pediatric Patients With Solid Tumors (3CAR)

CNSDermatologicGastrointestinalGenitourinarySarcoma

48 enrolled

Adrenal Cortex Neoplasms, Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT07584499 2026-05-13

MRG003

CNSGenitourinaryHead & NeckSarcoma

51 enrolled

Squamous Cell Carcinoma of Head and Neck, Nasopharyngeal Carcinoma, Medulloblastoma, Neoplasm Metastasis, Wilms Tumor, Neuroblastoma, Recurrence, Rhabdomyosarcoma, Rhabdoid Tumor

NCT06500819 2026-05-07

Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors

41 enrolled

Neuroblastoma, Sarcoma, Osteosarcoma

NCT04084067 2026-04-30

Indocyanine Green (ICG) Guided Tumor Resection

CNSGastrointestinalGenitourinaryLymphoidSarcoma

230 enrolled

Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Lymphoma, Neoplasms, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT03966651 2026-04-29

NEUROBLU 02

1 enrolled

Neuroblastoma

NCT02914405 2026-04-28

MiniVan

44 enrolled

Neuroblastoma

NCT04483778 2026-04-28

B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

CNSDermatologicGastrointestinalGenitourinaryOther solid neoplasmSarcoma

68 enrolled

Carcinoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT04837547 2026-04-28

PEACH

24 enrolled

Diffuse Intrinsic Pontine Glioma, Neuroblastoma

NCT05990751 2026-04-24

MAGNETO

12 enrolled

Neuroblastoma

NCT01953900 2026-04-22

VEGAS

26 enrolled

Chickenpox, Neuroblastoma, Osteosarcoma

NCT04308330 2026-04-15

NYMC195

CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Hepatoblastoma

NCT00083135 2026-04-14

N2000-01: Double Infusion of Iodine I 131 Metaiodobenzylguanidine Followed by Autologous Stem Cell Transplantation

Neuroblastoma

NCT00093353 2026-04-14

N2003-01: Irinotecan, Temozolomide, and Cefixime in Treating Young Patients With Recurrent or Resistant Neuroblastoma

Diarrhea, Neuroblastoma, Drug-Related Side Effects and Adverse Reactions

NCT00295919 2026-04-14

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma

80 enrolled

Neuroblastoma

NCT00509353 2026-04-14

N2004-06: Irinotecan and Vincristine With 131I-MIBG Therapy for Resistant/Relapsed High-Risk Neuroblastoma

26 enrolled

Neuroblastoma

NCT00646230 2026-04-14

IV Fenretinide

17 enrolled

Phase 1 Not yet recruiting

Neuroblastoma

NCT07518654 2026-04-08

ThINKK-01

12 enrolled

CNSLymphoidOther hematologic neoplasm

Paroxysmal nonkinesigenic dyskinesia, Leukemia, Neoplasm Metastasis, Neuroblastoma, Leukemia, Myeloid, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01822652 2026-04-06

GRAIN

11 enrolled

Neuroblastoma, Recurrence

NCT03721068 2026-03-27

Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

Gaucher Disease, Neuroblastoma, Osteosarcoma

NCT02298348 2026-03-23

N2013-02

Neuroblastoma, Recurrence

NCT02573896 2026-03-23

Immunotherapy of Relapsed Refractory Neuroblastoma With Expanded NK Cells

13 enrolled

Neuroblastoma

NCT02780128 2026-03-10

NEPENTHE

Phase 1 Terminated

66 enrolled

Neoplasms, Neuroblastoma

NCT06104488 2026-02-25

A Study of Avutometinib for People With Solid Tumor Cancers

23 enrolled

Brain Neoplasms, Neoplasms, Neuroblastoma, Central Nervous System Neoplasms, Neurofibroma, Plexiform

NCT02909777 2026-02-11

Trial of CUDC-907 in Children and Young Adults With Relapsed or Refractory Solid Tumors, CNS Tumors, or Lymphoma

26 enrolled

CNSLymphoid

Brain Neoplasms, Lymphoma, Neuroblastoma

NCT01625351 2026-02-06

A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas

CNSDermatologicGastrointestinalGenitourinaryLymphoidSarcoma

23 enrolled

Carcinoma, Renal Cell, Digestive System Neoplasms, Carcinoma, Hepatocellular, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Adenocarcinoma, Clear Cell, Rhabdoid Tumor

NCT07211737 2026-02-06

NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma

Phase 1 Not yet recruiting

27 enrolled

Neuroblastoma, Osteosarcoma

NCT05421897 2026-01-29

RAPID

11 enrolled

Phase 1 Not yet recruiting

Neoplasms, Neuroblastoma

NCT07358260 2026-01-22

B7-H3.CD28Z.CART in Solid Tumors

40 enrolled

Neuroblastoma

NCT00085930 2026-01-07

NESTLES

19 enrolled

Neuroblastoma

NCT05650749 2025-12-29

GPC2

45 enrolled

CNSOther solid neoplasm

Neuroblastoma, Retinoblastoma

NCT05400603 2025-12-26

Aflac-NBL-2002

24 enrolled

Neuroblastoma, Osteosarcoma

NCT07007117 2025-12-26

PHOX2B

38 enrolled

Neuroblastoma

NCT03618381 2025-11-20

EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

44 enrolled

Carcinoma, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Hepatoblastoma, Sarcoma, Clear Cell, Neurofibrosarcoma, Rhabdoid Tumor, Desmoplastic Small Round Cell Tumor

NCT02508038 2025-10-16

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors

CNSLymphoidMyeloidOther hematologic neoplasmSarcoma

22 enrolled

Hodgkin Disease, Lymphoma, Non-Hodgkin, Myelodysplastic Syndromes, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Leukemia, Myeloid, Acute, Neuroectodermal Tumors, Primitive, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT03294954 2025-09-19

GINAKIT2

70 enrolled

Neuroblastoma

NCT03107988 2025-09-15

NANT 2015-02: A Phase 1 Study of Lorlatinib (PF-06463922)

65 enrolled 38 charts

Neuroblastoma

NCT02650648 2025-07-30

Humanized Anti-GD2 Antibody Hu3F8 and Allogeneic Natural Killer Cells for High-Risk Neuroblastoma

85 enrolled

Neuroblastoma

NCT03635632 2025-07-25

C7R-GD2.CART Cells for Patients With Relapsed or Refractory Neuroblastoma and Other GD2 Positive Cancers (GAIL-N)

BreastCNSDermatologicSarcoma

94 enrolled

Uveal Melanoma, Breast Neoplasms, Phyllodes Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma

NCT07027748 2025-07-14

Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma

Neuroblastoma

NCT06485947 2025-07-08

DBPilot

38 enrolled

Neuroblastoma

NCT03332667 2025-04-16

MIBG With Dinutuximab +/- Vorinostat

45 enrolled 16 charts

Neuroblastoma

NCT00638898 2025-03-20

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

25 enrolled

CNSGenitourinarySarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT04239040 2025-03-19

GVAX Plus Checkpoint Blockade in Neuroblastoma

Phase 1 Terminated

19 enrolled

Neuroblastoma

NCT06631391 2025-02-20

Phase I Study of Umbilical Cord Blood Natural Killer (NK) Cell Therapy for Children With High-risk, R/R Neuroblastoma.

Neuroblastoma

NCT02030964 2025-02-17

DFMO

Neuroblastoma

NCT06751134 2025-02-07

Chimeric Natural Killer Receptor-Universal T Cells for Relapsed or Refractory Neuroblastoma

12 enrolled

Neuroblastoma, Recurrence

NCT02076906 2025-01-01

MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors

CNSGastrointestinalGenitourinarySarcoma

7 enrolled

Carcinoma, Hepatocellular, Neoplasms, Germ Cell and Embryonal, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma, Desmoid Tumors

NCT00002730 2024-11-20

Chemotherapy in Treating Children With Neuroblastoma