Clinical Trials

CNSDermatologicGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Neuroblastoma, Ganglioneuroblastoma

NCT04851119 2026-05-05

Tegavivint for the Treatment of Recurrent or Refractory Solid Tumors, Including Lymphomas and Desmoid Tumors

Phase 1/2 Recruiting

147 enrolled

Carcinoma, Hepatocellular, Lymphoma, Non-Hodgkin, Melanoma, Wilms Tumor, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Ewing, Osteosarcoma, Colorectal Neoplasms, Endometrial Neoplasms, Hepatoblastoma, Desmoid Tumors

NCT03126916 2026-02-27

Testing the Addition of 131I-MIBG or Lorlatinib to Intensive Therapy in People With High-Risk Neuroblastoma (NBL)

Phase 3 Recruiting

750 enrolled

Phase 2 Active not recruiting

Neuroblastoma, Ganglioneuroblastoma

NCT03794349 2026-02-18

Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma

94 enrolled 14 charts

Neuroblastoma

NCT01175356 2026-01-23

Induction Therapy Including 131 I-MIBG and Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma Undergoing Stem Cell Transplant, Radiation Therapy, and Maintenance Therapy With Isotretinoin

99 enrolled 11 charts

Neuroblastoma, Ganglioneuroblastoma

NCT03057626 2026-01-09

Late Effects After Treatment in Patients With Previously Diagnosed High-Risk Neuroblastoma

Active not recruiting

376 enrolled

Neuroblastoma

NCT00904241 2025-11-13

Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma

Active not recruiting

10,000 enrolled

Phase 2 Active not recruiting

Neuroblastoma, Ganglioneuroblastoma

NCT04385277 2025-10-27

Treatment With Dinutuximab, Sargramostim (GM-CSF), and Isotretinoin in Combination With Irinotecan and Temozolomide After Intensive Therapy for People With High-Risk Neuroblastoma (NBL)

41 enrolled 13 charts

Neuroblastoma, Ganglioneuroblastoma

NCT00898755 2025-05-02

Collecting and Storing Tissue From Young Patients With Cancer

CNSLymphoidOther hematologic neoplasmOther solid neoplasmSarcoma

213 enrolled

Leukemia, Lymphoma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Neuroblastoma, Retinoblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Leukemia, Myeloid, Acute, Central Nervous System Neoplasms, Rhabdoid Tumor, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01798004 2024-07-15

Busulfan, Melphalan, and Stem Cell Transplant After Chemotherapy in Treating Patients With Newly Diagnosed High-Risk Neuroblastoma

150 enrolled 9 charts

Neuroblastoma, Ganglioneuroblastoma

NCT01606878 2024-01-05

Crizotinib and Combination Chemotherapy in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

46 enrolled 24 charts

CNSLymphoid

Neuroblastoma, Lymphoma, Large-Cell, Anaplastic

NCT00716976 2023-11-09

Sodium Thiosulfate in Preventing Hearing Loss in Young Patients Receiving Cisplatin for Newly Diagnosed Germ Cell Tumor, Hepatoblastoma, Medulloblastoma, Neuroblastoma, Osteosarcoma, or Other Malignancy

131 enrolled 18 charts 1 FDA

CNSGastrointestinalGenitourinaryGynecologicSarcoma

Ovarian Germ Cell Cancer, Ototoxicity, Brain Neoplasms, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Hepatoblastoma

NCT00033293 2023-04-18

Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma

53 enrolled 14 charts

Neuroblastoma

NCT00567567 2022-04-28

Comparing Two Different Myeloablation Therapies in Treating Young Patients Who Are Undergoing a Stem Cell Transplant for High-Risk Neuroblastoma

665 enrolled 26 charts

Neuroblastoma

NCT02013336 2022-03-31

Phase 1 Dose-escalating Study of MM-398 (Irinotecan Sucrosofate Liposome Injection) Plus Intravenous Cyclophosphamide in Recurrent or Refractory Pediatric Solid Tumors

Phase 1 Unknown

30 enrolled

CNSSarcoma

Neuroblastoma, Recurrence, Rhabdomyosarcoma, Sarcoma, Ewing, Osteosarcoma

NCT02163356 2022-03-31

SPOC2013-001

Phase 1 Terminated

4 enrolled

Neuroblastoma, Recurrence

NCT02075177 2022-03-21

Expanded Access Study of Fenretinide Lym-X-Sorb Plus Ketoconazole in Neuroblastoma

No longer available

Neuroblastoma

NCT02452554 2022-01-13

Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma

62 enrolled 15 charts

CNSGenitourinarySarcoma

Pleuropulmonary blastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Synovial, Neurofibrosarcoma

NCT00499616 2021-07-06

Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma

464 enrolled 25 charts

Neuroblastoma

NCT01916187 2020-09-21

Imetelstat Given Intravenously Alone and With Standard 13-Cis-Retinoic Acid in Children With Neuroblastoma

Phase 1 Withdrawn

122 enrolled 24 charts 2 FDA

Neuroblastoma

NCT00939770 2020-06-09

Crizotinib in Treating Younger Patients With Relapsed or Refractory Solid Tumors or Anaplastic Large Cell Lymphoma

Phase 1/2 Completed

CNSLymphoid

Neuroblastoma, Lymphoma, Large-Cell, Anaplastic

NCT01154816 2020-05-13

Alisertib in Treating Young Patients With Recurrent or Refractory Solid Tumors or Leukemia

CNSGastrointestinalLymphoidOther hematologic neoplasmSarcoma

118 enrolled 24 charts

Neuroblastoma, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT01334515 2019-10-21

Biological Therapy, Sargramostim, and Isotretinoin in Treating Patients With Relapsed or Refractory Neuroblastoma

52 enrolled 11 charts

Neuroblastoma

NCT00436852 2019-07-17

ABT-751 in Treating Children With Neuroblastoma That Has Relapsed or Not Responded to Previous Treatment

92 enrolled 17 charts

Neuroblastoma

NCT01119560 2019-01-08

Genetic Susceptibility Biomarkers in Children With Neuroblastoma (Also Known as Neuroblastoma Epidemiology in North America [NENA])

576 enrolled

Neuroblastoma

NCT00436696 2018-08-07

Genetic Analysis Using Blood or Bone Marrow From Participants With Neuroblastoma or Noncancerous Conditions

9,350 enrolled

CNSGastrointestinalSarcoma

Neuroblastoma

NCT02011126 2018-08-07

Imetelstat Sodium in Treating Younger Patients With Relapsed or Refractory Solid Tumors

Phase 2 Withdrawn

Neuroblastoma, Rhabdomyosarcoma, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral

NCT00309907 2017-09-29

Etanercept in Treating Young Patients With Idiopathic Pneumonia Syndrome After Undergoing a Donor Stem Cell Transplant

CNSGenitourinaryLymphoidOther hematologic neoplasmSarcoma

39 enrolled 12 charts

Blast Crisis, Burkitt Lymphoma, Wilms Tumor, Neuroblastoma, Recurrence, Leukemia, Myeloid, Accelerated Phase, Leukemia, Myeloid, Chronic-Phase, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

NCT00003119 2017-03-13

Surgery in Treating Children With Neuroblastoma

968 enrolled

Neuroblastoma

NCT01353300 2016-07-11

Gene Mutation in Samples From Young Patients With Pleuropulmonary Blastoma Syndrome at Risk for Developing Cancer

CNSGastrointestinalGenitourinarySarcoma

31 enrolled

Pleuropulmonary blastoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma

NCT01493830 2016-07-11

Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma

5 enrolled

Neuroblastoma

NCT01510600 2016-05-19

Studying Biomarkers in Samples From Patients With High-Risk Neuroblastoma

99 enrolled

Neuroblastoma

NCT00898391 2016-05-18

Study of DNA in Blood Samples From Patients With Neuroblastoma

329 enrolled

Neuroblastoma

NCT01169376 2016-05-18

Biomarkers in Young Patients With Neuroblastoma

380 enrolled

Neuroblastoma

NCT01387724 2016-05-18

Biomarkers in Blood and Tissue Samples From Patients With Newly Diagnosed Neuroblastoma

300 enrolled

Neuroblastoma

NCT01553448 2016-05-18

Studying Gene Expression in Samples From Younger Patients With Neuroblastoma

75 enrolled

Neoplasms, Neuroblastoma

NCT01589341 2016-05-18

Studying Chromosomes in Samples From Younger Patients With Neuroblastoma

300 enrolled

Neuroblastoma

NCT01407731 2016-05-17

Protein Expression in Human Neuroblastoma Tumor Samples

20 enrolled

Neuroblastoma

NCT01520233 2016-05-17

Gene Expression in Predicting Outcome in Samples From Patients With High-Risk Neuroblastoma

100 enrolled

Neuroblastoma

NCT01358604 2016-04-15

Biomarkers in Samples From Young Patients With Neuroblastoma

20 enrolled

Neuroblastoma

NCT02444884 2016-02-09

MLN8237 to Treat Children With Relapsed/Refractory Solid Tumors

54 enrolled