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Phase

Phase 1/2 2Phase 2 1

Status

Recruiting 1Completed 1Active not recruiting 1

Sponsor Class

NIH 4OTHER 3INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 2Genitourinary 2CNS 2Head & Neck 1Gynecologic 1Gastrointestinal 1

Conditions

Glioblastoma 264Glioma 109Brain Neoplasms 104Gliosarcoma 85Central Nervous System Neoplasms 64Astrocytoma 61Melanoma 46Oligodendroglioma 44Neuroblastoma 28Recurrence 22Neoplasm Metastasis 18Neoplasms 16Medulloblastoma 16Ependymoma 16Sarcoma, Ewing 13Lymphoma 13Sarcoma 12Rhabdomyosarcoma 11Neuroendocrine Tumors 11Lung Neoplasms 11Diffuse Intrinsic Pontine Glioma 10Small Cell Lung Carcinoma 9Neuroectodermal Tumors, Primitive 7Colorectal Neoplasms 7Unspecified Adult Solid Tumor, Protocol Specific 6Osteosarcoma 6Pinealoma 5Optic Nerve Glioma 5Choroid Plexus Neoplasms 5Carcinoma, Non-Small-Cell Lung 5

Interventions

Filgrastim 13Peripheral Blood Stem Cell Transplantation 10Melphalan 9Ifosfamide 9Etoposide 9Cyclophosphamide 8Thiotepa 6Carboplatin 6Busulfan 6Radiotherapy 5Doxorubicin 5Vincristine 3Topotecan 3Temozolomide 3Docetaxel 3trioctyl phosphine oxide 2temsirolimus 2etoposide phosphate 2Transplantation 2Surgical Procedures, Operative 2Stem Cell Transplantation 2Radiotherapy, Intensity-Modulated 2Microarray Analysis 2Mesna 2Granulocyte Colony-Stimulating Factor 2Gemcitabine 2Dexrazoxane 2Cisplatin 2Bone Marrow Transplantation 2Amifostine 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Neuroectodermal Tumors, Primitive, Peripheral × Temozolomide × Clear all
NCT04901702 2026-05-19

Study of Onivyde With Talazoparib or Temozolomide in Children With Recurrent Solid Tumors and Ewing Sarcoma

St. Jude Children's Research Hospital

Phase 1/2 Recruiting
90 enrolled
CNSGastrointestinalGenitourinarySarcoma

Neoplasms, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor

NCT01946529 2026-02-23

Therapeutic Trial for Patients With Ewing Sarcoma Family of Tumor and Desmoplastic Small Round Cell Tumors

St. Jude Children's Research Hospital

Phase 2 Active not recruiting
24 enrolled 11 charts

Neuroectodermal Tumors, Primitive, Peripheral, Desmoplastic Small Round Cell Tumor

NCT00005952 2013-06-20

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Duke University

Phase 1/2 Completed
30 enrolled
CNSGenitourinaryGynecologicHead & NeckSarcoma

Familial ependymoma, Testicular Germ Cell Tumor, Astrocytoma, Head and Neck Neoplasms, Kidney Neoplasms, Medulloblastoma, Nasopharyngeal Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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