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Phase

Phase 1/2 1

Status

Recruiting 1Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Breast Neoplasms 9Prostatic Neoplasms 5Neoplasms 5Neoplasm Metastasis 4Advanced Solid Tumors 4Leukemia, Myeloid, Acute 3Triple Negative Breast Neoplasms 2Pancreatic Neoplasms 2Ovarian Neoplasms 2Carcinoma, Renal Cell 2Solid Tumor 1Small Cell Lung Carcinoma 1Sarcoma, Ewing 1Recurrent Squamous Cell Lung Carcinoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Myelodysplastic Syndromes 1Lymphoma, Mantle-Cell 1Lung Neoplasms 1Leukemia, Lymphocytic, Chronic, B-Cell 1Kidney Neoplasms 1Glioma 1Glioblastoma 1Fanconi Anemia, Complementation Group D1 1Fallopian Tube Neoplasms 1Colorectal Neoplasms 1Childhood Solid Tumors 1Central Nervous System Neoplasms 1Carcinoma, Ovarian Epithelial 1Breast Adenocarcinoma 1Advanced Solid Tumor 1

Interventions

Filgrastim 18Cyclophosphamide 13Etoposide 12Peripheral Blood Stem Cell Transplantation 11Ifosfamide 11Vincristine 9Carboplatin 9Radiotherapy 8Doxorubicin 8Melphalan 7Topotecan 6Temozolomide 5Granulocyte Colony-Stimulating Factor 5Busulfan 5Thiotepa 4Irinotecan 4Docetaxel 4trioctyl phosphine oxide 3cixutumumab 3Imatinib Mesylate 3Amifostine 3tanespimycin 2pegfilgrastim 2ixabepilone 2etoposide phosphate 2Oxaliplatin 2Neoadjuvant Therapy 2Microarray Analysis 2Mesna 2Magnetic Resonance Spectroscopy 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Completed × Neuroectodermal Tumors, Primitive, Peripheral × talazoparib × Clear all
NCT02116777 2021-03-26

Talazoparib and Temozolomide in Treating Younger Patients With Refractory or Recurrent Malignancies

National Cancer Institute (NCI)

Phase 1/2 Completed
40 enrolled 32 charts
CNS

Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral

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