Announcements Trials
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Phase

Phase 1 2

Status

Recruiting 1Not yet recruiting 1

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Leukemia, Myeloid, Acute 96Precursor Cell Lymphoblastic Leukemia-Lymphoma 61Myelodysplastic Syndromes 52Recurrence 37Leukemia, Lymphocytic, Chronic, B-Cell 37Multiple Myeloma 36Lymphoma, Non-Hodgkin 35Lymphoma 34Lymphoma, B-Cell 29Hematologic Neoplasms 28Lymphoma, Follicular 24Lymphoma, Large B-Cell, Diffuse 23Lymphoma, Mantle-Cell 22Leukemia 22Melanoma 21Lymphoma, B-Cell, Marginal Zone 20Myeloproliferative Disorders 19Leukemia, Myelogenous, Chronic, BCR-ABL Positive 19Leukemia, Biphenotypic, Acute 18Hodgkin Disease 18Ovarian Neoplasms 17Burkitt Lymphoma 17Pancreatic Neoplasms 16Neoplasms 13Neoplasm Metastasis 12Leukemia, Myelomonocytic, Chronic 12Colorectal Neoplasms 11Anemia, Refractory, with Excess of Blasts 11Stomach Neoplasms 10Carcinoma, Non-Small-Cell Lung 10

Interventions

Cyclophosphamide 6Vincristine 3Temozolomide 3Radiotherapy 3Cisplatin 3Automobiles 3fludarabine 2Etoposide 2Eflornithine 2Carboplatin 2omburtamab I-131 1ibrutinib 1gallium Ga 68 dotatate 1etoposide phosphate 1belzutifan 1Zoledronic Acid 1Thiotepa 1Tamoxifen 1Standard of Care 1Radiotherapy, Image-Guided 1Pemetrexed 1ONC206 1Nivolumab 1Mesna 1Maintenance Chemotherapy 1Lomustine 1Isotretinoin 1Induction Chemotherapy 1Hydrocortisone 1HhAntag691 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Neuroectodermal Tumors, Primitive × fludarabine × 1 year × Clear all
NCT07390539 2026-02-05

B7-H3.CD28Z.CART in CNS Neoplasms

Dana-Farber Cancer Institute

Phase 1 Not yet recruiting
70 enrolled
CNS

Brain Neoplasms, Ependymoma, Medulloblastoma, Meningeal Neoplasms, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

NCT07087002 2026-01-27

GPC2-CAR T Cell Therapy for Relapsed or Refractory Medulloblastoma in Children and Young Adults

Stanford University

Phase 1 Recruiting
18 enrolled
CNS

Brain Neoplasms, Medulloblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor

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