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Phase

Phase 2 1Phase 1/2 1

Status

Completed 2

Sponsor Class

NIH 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Colonic Neoplasms 32Rectal Neoplasms 31Colorectal Neoplasms 27Unspecified Adult Solid Tumor, Protocol Specific 15Stomach Neoplasms 10Neoplasm Metastasis 7Lung Neoplasms 6Neuroblastoma 5Small Cell Lung Carcinoma 4Pancreatic Neoplasms 4Medulloblastoma 4Lymphoma, Large B-Cell, Diffuse 4Burkitt Lymphoma 4Unspecified Childhood Solid Tumor, Protocol Specific 3Sezary Syndrome 3Sarcoma 3Rhabdomyosarcoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Neuroectodermal Tumors, Primitive, Peripheral 3Mycosis Fungoides 3Lymphoma, T-Cell, Cutaneous 3Lymphoma, Non-Hodgkin 3Lymphoma, Mantle-Cell 3Lymphoma, Large-Cell, Immunoblastic 3Lymphoma, Large-Cell, Anaplastic 3Lymphoma, Follicular 3Lymphoma, B-Cell, Marginal Zone 3Liver Neoplasms 3Leukemia, Lymphocytic, Chronic, B-Cell 3

Interventions

Temozolomide 3Vincristine 2Irinotecan 2Cyclophosphamide 2veliparib 1gallium Ga 68 dotatate 1entinostat 1carboxyamido-triazole 1adavosertib 1Verteporfin 1Surgical Procedures, Operative 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1Paclitaxel 1Methotrexate 1Magnetic Resonance Spectroscopy 1Lenalidomide 1Immunoglobulin G 1Filgrastim 1Etoposide 1Erlotinib Hydrochloride 1Doxorubicin 1Disulfides 1Congresses as Topic 1Cisplatin 1Chemotherapy, Adjuvant 1Carmustine 1Bevacizumab 12-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Neuroectodermal Tumors, Primitive × Irinotecan × Clear all
NCT02095132 2023-09-26

Adavosertib and Irinotecan Hydrochloride in Treating Younger Patients With Relapsed or Refractory Solid Tumors

National Cancer Institute (NCI)

Phase 1/2 Completed
76 enrolled 25 charts
CNSSarcoma

Medulloblastoma, Neuroblastoma, Pinealoma, Rhabdomyosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive

NCT01217437 2021-07-23

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

National Cancer Institute (NCI)

Phase 2 Completed
108 enrolled 14 charts
CNS

Medulloblastoma, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive

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