Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Completed 3

Sponsor Class

OTHER 7NIH 3NETWORK 1

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1

Conditions

Glioblastoma 31Gliosarcoma 27Astrocytoma 22Brain Neoplasms 17Central Nervous System Neoplasms 16Oligodendroglioma 12Medulloblastoma 9Neuroblastoma 7Glioma 7Choroid Plexus Neoplasms 7Sarcoma 6Melanoma 6Familial ependymoma 6Optic Nerve Glioma 5Spinal Cord Neoplasms 4Rhabdoid Tumor 4Neuroectodermal Tumors, Primitive, Peripheral 4Ependymoma 4Uveal Melanoma 3Rhabdomyosarcoma 3Ovarian Neoplasms 3Osteosarcoma 3Neuroectodermal Tumors, Primitive 3Breast Neoplasms 3Wilms Tumor 2Testicular Neoplasms 2Teratoma 2Small Cell Lung Carcinoma 2Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Pinealoma 2

Interventions

Temozolomide 3Vincristine 2Irinotecan 2Cyclophosphamide 2veliparib 1gallium Ga 68 dotatate 1entinostat 1carboxyamido-triazole 1adavosertib 1Verteporfin 1Surgical Procedures, Operative 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1Paclitaxel 1Methotrexate 1Magnetic Resonance Spectroscopy 1Lenalidomide 1Immunoglobulin G 1Filgrastim 1Etoposide 1Erlotinib Hydrochloride 1Doxorubicin 1Disulfides 1Congresses as Topic 1Cisplatin 1Chemotherapy, Adjuvant 1Carmustine 1Bevacizumab 12-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
NIH × Neuroectodermal Tumors, Primitive × Temozolomide × Clear all
NCT01217437 2021-07-23

Temozolomide and Irinotecan Hydrochloride With or Without Bevacizumab in Treating Young Patients With Recurrent or Refractory Medulloblastoma or CNS Primitive Neuroectodermal Tumors

National Cancer Institute (NCI)

Phase 2 Completed
108 enrolled 14 charts
CNS

Medulloblastoma, Pinealoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive

NCT00994071 2019-12-09

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
9 enrolled
CNS

Astrocytoma, Brain Neoplasms, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

NCT01119599 2015-09-29

RO4929097, Temozolomide, and Radiation Therapy in Treating Patients With Newly Diagnosed Malignant Glioma

National Cancer Institute (NCI)

Phase 1 Completed
22 enrolled
CNSSarcoma

Astrocytoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neuroma, Acoustic, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

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