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Phase

Phase EARLY_PHASE1 1

Status

Completed 2Active not recruiting 2Recruiting 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 19Burkitt Lymphoma 17Lymphoma, Large B-Cell, Diffuse 12Neuroblastoma 7Lymphoma, Follicular 7Lymphoma, B-Cell 7Leukemia, Biphenotypic, Acute 7Rhabdomyosarcoma 6Lymphoma, T-Cell, Peripheral 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 5Sarcoma, Ewing 4Lymphoma 4Retinoblastoma 3Recurrence 3Precursor B-Cell Lymphoblastic Leukemia-Lymphoma 3Osteosarcoma 3Medulloblastoma 3Lymphoma, T-Cell 3Lymphoma, Non-Hodgkin 3Wilms Tumor 2Sarcoma 2Plasmablastic Lymphoma 2Lymphoma, B-Cell, Marginal Zone 2Leukemia, B-Cell 2Hodgkin Disease 2Ganglioneuroblastoma 2Blastic Plasmacytoid Dendritic Cell Neoplasm 2Stage I Mixed Cell Type Kidney Wilms Tumor 1Rhabdomyosarcoma, Embryonal 1Rhabdoid Tumor 1

Interventions

Temozolomide 3Cyclophosphamide 3Etoposide 2ibrutinib 1gallium Ga 68 dotatate 1fludarabine 1etoposide phosphate 1belzutifan 1Zoledronic Acid 1Vincristine 1Thiotepa 1Tamoxifen 1Standard of Care 1Radiotherapy 1ONC206 1Nivolumab 1Mesna 1Isotretinoin 1Hydrocortisone 1Granulocyte Colony-Stimulating Factor 1Filgrastim 1Eflornithine 1Drug Therapy 1Cisplatin 1Celecoxib 1Carboplatin 1Blood Specimen Collection 1Automobiles 11-methyltryptophan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Recruiting × Neuroectodermal Tumors, Primitive × Vincristine × Clear all
NCT06942039 2026-02-27

Pilot Study of IT Topotecan and Maintenance Chemotherapy for HR-EBTs in Children < 6 Years, Post Consolidation

C17 Council

Phase EARLY_PHASE1 Recruiting
15 enrolled
CNS

Medulloblastoma, Neuroblastoma, Pinealoma, Neuroectodermal Tumors, Primitive, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

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