Announcements Trials
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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

CNS 1

Conditions

Breast Neoplasms 10Ovarian Neoplasms 9Fallopian Tube Neoplasms 8Triple Negative Breast Neoplasms 7Pancreatic Neoplasms 5Neoplasms 4Astrocytoma 4Precursor Cell Lymphoblastic Leukemia-Lymphoma 3Neoplasm Metastasis 3Lymphoma 3Leukemia, Myelomonocytic, Chronic 3Leukemia, Myeloid, Acute 3Glioblastoma 3Uterine Cervical Neoplasms 2Thrombocythemia, Essential 2Small Cell Lung Carcinoma 2Rectal Neoplasms 2Prostatic Neoplasms 2Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 2Polycythemia Vera 2Medulloblastoma 2Lymphoma, Follicular 2Leukemia, Myelomonocytic, Acute 2Leukemia, Lymphocytic, Chronic, B-Cell 2Hereditary Breast and Ovarian Cancer Syndrome 2Gliosarcoma 2Carcinoma, Non-Small-Cell Lung 2Burkitt Lymphoma 2Breast Neoplasms, Male 2Brain Neoplasms 2

Interventions

Temozolomide 3Vincristine 2Irinotecan 2Cyclophosphamide 2veliparib 1gallium Ga 68 dotatate 1entinostat 1carboxyamido-triazole 1adavosertib 1Verteporfin 1Surgical Procedures, Operative 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiotherapy 1Paclitaxel 1Methotrexate 1Magnetic Resonance Spectroscopy 1Lenalidomide 1Immunoglobulin G 1Filgrastim 1Etoposide 1Erlotinib Hydrochloride 1Doxorubicin 1Disulfides 1Congresses as Topic 1Cisplatin 1Chemotherapy, Adjuvant 1Carmustine 1Bevacizumab 12-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
NIH × Neuroectodermal Tumors, Primitive × veliparib × Clear all
NCT00994071 2019-12-09

A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors

National Institutes of Health Clinical Center (CC)

Phase 1 Completed
9 enrolled
CNS

Astrocytoma, Brain Neoplasms, Ependymoma, Medulloblastoma, Neuroectodermal Tumors, Primitive

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