Announcements Trials
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Phase

Phase 2 2

Status

Recruiting 1Active not recruiting 1

Sponsor Class

INDUSTRY 9NIH 6OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Breast Neoplasms 852Neoplasms 643Prostatic Neoplasms 439Lung Neoplasms 359Colorectal Neoplasms 327Carcinoma, Non-Small-Cell Lung 318Leukemia, Myeloid, Acute 251Pancreatic Neoplasms 218Brain Neoplasms 202Multiple Myeloma 198Neoplasm Metastasis 191Carcinoma, Hepatocellular 178Head and Neck Neoplasms 176Glioblastoma 167Precursor Cell Lymphoblastic Leukemia-Lymphoma 166Melanoma 153Ovarian Neoplasms 149Squamous Cell Carcinoma of Head and Neck 148Rectal Neoplasms 134Recurrence 132Hematologic Neoplasms 125Sarcoma 124Uterine Cervical Neoplasms 117Stomach Neoplasms 116Carcinoma, Renal Cell 115Triple Negative Breast Neoplasms 114Glioma 114Motor Activity 100Myelodysplastic Syndromes 96Esophageal Neoplasms 96

Interventions

trametinib 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Neurofibroma, Plexiform × 90 days × Clear all
NCT06188741 2026-05-29

NF114

University of Alabama at Birmingham

Phase 2 Recruiting
200 enrolled
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03363217 2026-04-24

Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway.

St. Justine's Hospital

Phase 2 Active not recruiting
114 enrolled
CNS

Brain Neoplasms, Glioma, Neurofibromatosis 1, Neurofibroma, Plexiform

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