Announcements Trials
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Phase

Phase 2 5Phase 1/2 2Phase 1 2Phase 3 1

Status

Completed 1Active not recruiting 1

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Neurofibromatosis 1 5Carcinoma, Non-Small-Cell Lung 3Pancreatic Neoplasms 2Neurofibroma, Plexiform 2Triple Negative Breast Neoplasms 1Sarcoma, Kaposi 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Pain 1Optic Nerve Glioma 1Neurofibrosarcoma 1Neoplasms 1Lung Neoplasms 1Liver Neoplasms 1Gastrointestinal Neoplasms 1Colorectal Neoplasms 1Carcinoma, Hepatocellular 1Astrocytoma 1Acquired Immunodeficiency Syndrome 1AIDS-related Kaposi sarcoma 1

Interventions

AZD 6244 2trametinib 1dabrafenib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Neurofibroma, Plexiform × AZD 6244 × Clear all
NCT01362803 2026-06-01

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

National Institutes of Health Clinical Center (CC)

Phase 1/2 Active not recruiting
99 enrolled 1 FDA
CNS

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT03326388 2024-04-04

INSPECT

Great Ormond Street Hospital for Children NHS Foundation Trust

Phase 1/2 Completed
14 enrolled
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform, Optic Nerve Glioma

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