Announcements Trials
Browse Landscape

Phase

Phase 2 2Phase 1 1

Status

Completed 2

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2

Conditions

Neurofibroma, Plexiform 2Squamous Cell Carcinoma of Head and Neck 1Neurofibromatosis 1 1Neurofibromatoses 1Nerve Sheath Neoplasms 1Myofibroma 1Lymphedema 1Lung Neoplasms 1Leiomyoma 1Colorectal Neoplasms 1Breast Neoplasms 1Acute Lung Injury 1

Interventions

AZD 6244 5trametinib 2pirfenidone 2Imatinib Mesylate 2tipifarnib 1peginterferon alfa-2b 1mirdametinib 1cediranib 1cabozantinib 1binimetinib 1Vinblastine 1Methotrexate 1Everolimus 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 2 × Neurofibroma, Plexiform × pirfenidone × Clear all
NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
36 enrolled 13 charts
CNS

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00754780 2012-03-19

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

Mayo Clinic

Phase 2 Completed
24 enrolled
CNS

Neurofibromatoses, Neurofibroma, Plexiform

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