Announcements Trials
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Phase

Phase 2 1Phase 1 1

Status

Completed 2

Sponsor Class

NIH 2OTHER 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Other neoplasm 1

Conditions

Neurofibromatosis 1 2Neurofibroma, Plexiform 2Radiation Fibrosis Syndrome 1Precancerous Conditions 1Nerve Sheath Neoplasms 1Myofibroma 1Leiomyoma 1

Interventions

AZD 6244 3pirfenidone 2tipifarnib 1cediranib 1Surveys and Questionnaires 1Sorafenib 1Pharmacokinetics 1Acceptance and Commitment Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
NIH × Neurofibroma, Plexiform × pirfenidone × Clear all
NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

National Institutes of Health Clinical Center (CC)

Phase 2 Completed
36 enrolled 13 charts
CNS

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00053937 2015-04-30

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas

National Cancer Institute (NCI)

Phase 1 Completed
CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

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