Clinical Trials Browser

Phase 1/2 × Interventional × Neurofibroma, Plexiform × Clear all

NCT01362803 2026-05-22

AZD6244 Hydrogen Sulfate for Children With Nervous System Tumors

Phase 1/2 Active not recruiting

99 enrolled 1 FDA

Neurofibromatosis 1, Pain, Neurofibroma, Plexiform

NCT07024394 2025-06-17

Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1

Phase 1/2 Not yet recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT04954001 2024-11-12

Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1

Phase 1/2 Active not recruiting

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03326388 2024-04-04

INSPECT

Phase 1/2 Completed

Neurofibromatosis 1, Neurofibroma, Plexiform, Optic Nerve Glioma

NCT02124772 2021-07-14

Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations

Phase 1/2 Completed

139 enrolled 42 charts 1 FDA

Histiocytosis, Langerhans-Cell, Neoplasms, Neuroblastoma, Neurofibroma, Plexiform