Clinical Trials

Phase 1 Not yet recruiting

Brain Neoplasms, Glioma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06502171 2026-03-12

NF113

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06104488 2026-02-25

A Study of Avutometinib for People With Solid Tumor Cancers

Phase 1 Recruiting

23 enrolled

Brain Neoplasms, Neoplasms, Neuroblastoma, Central Nervous System Neoplasms, Neurofibroma, Plexiform

NCT06515860 2026-01-09

NF1-TED

Recruiting

1,000 enrolled

CNSSarcoma

Neurofibromatosis 1, Neurofibroma, Plexiform, Neurofibrosarcoma

NCT05238909 2025-09-02

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

Enrolling by invitation

200 enrolled

Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02777775 2025-07-24

Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.

Completed

71 enrolled

CNSDermatologic

Neurofibromatosis 1, Skin Neoplasms, Neurofibroma, Plexiform

NCT03231306 2025-05-02

NF108-BINI

45 enrolled 8 charts

Phase 2 Not yet recruiting

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT06763315 2025-01-08

LS-NF1PNs

50 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06379230 2024-04-23

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Unknown

2,000 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03741101 2024-04-11

plexifpc

Phase 2 Unknown

15 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03326388 2024-04-04

INSPECT

Phase 1/2 Completed

14 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform, Optic Nerve Glioma

NCT05199376 2024-02-09

CryoNF1

Phase NA Recruiting

Neurofibroma, Neurofibroma, Plexiform

NCT02101736 2023-05-24

NF105-CABO

45 enrolled 10 charts

Neurofibromatoses, Neurofibroma, Plexiform

NCT01800032 2021-05-12

PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)

Completed

Phase NA Active not recruiting

Neurofibroma, Plexiform, Optic Nerve Glioma

NCT03820778 2021-03-02

Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1

10 enrolled

Neurofibromatosis, type 4, of Riccardi, Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03688568 2021-02-12

Study of Imatinib in Children With Neurofibromatosis and Airway Tumors

Phase 2 Withdrawn

Neurofibroma, Plexiform

NCT02177825 2019-04-08

Study of Imatinib Mesylate in Neurofibromatosis Type I Patients Aged 2 to 21 With Plexiform Neurofibromas

Phase 2 Terminated

5 enrolled

Neurofibroma, Plexiform

NCT00030264 2018-08-08

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

23 enrolled 9 charts

CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT01402817 2018-03-14

Study of Sutent®/Sunitinib (SU11248) in Subjects With NF-1 Plexiform Neurofibromas

Phase 2 Terminated

19 enrolled 8 charts

Neurofibromatoses, Neurofibroma, Plexiform

NCT00396019 2017-11-06

Study of PEG-Intron for Plexiform Neurofibromas

86 enrolled 6 charts

Phase EARLY_PHASE1 Completed

Neurofibroma, Plexiform

NCT01275586 2017-04-12

Study of Tasigna®/Nilotinib (AMN107) in Neurofibromatosis (NF1) Patients With Plexiform Neurofibromas

6 enrolled 7 charts

Neurofibroma, Neurofibromatoses, Neurofibroma, Plexiform

NCT01412892 2014-11-14

NFitor

Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT00060008 2014-04-04

Fludeoxyglucose F 18 Positron Emission Tomography and Magnetic Resonance Perfusion Imaging in Patients With Neurofibromatosis 1 and Plexiform Neurofibroma

Phase NA Terminated

18 enrolled 4 charts

CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT00754780 2012-03-19

Clinical Trial of Pirfenidone in Adult Patients With Neurofibromatosis 1

24 enrolled