Clinical Trials

Neurofibroma, Plexiform

NCT06360406 2026-04-30

Real-World Treatment Study of Koselugo (Selumetinib)

200 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02544022 2026-04-24

Development and Validation of Patient Reported Outcome (PRO) Measures for Individuals With Neurofibromatosis 1 (NF1) and Plexiform Neurofibromas (pNFs)

476 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06515860 2026-01-09

NF1-TED

1,000 enrolled

CNSSarcoma

Neurofibromatosis 1, Neurofibroma, Plexiform, Neurofibrosarcoma

NCT06222203 2025-09-26

Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)

225 enrolled

CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform, Neurofibrosarcoma

NCT05238909 2025-09-02

Developing Biomarkers of Plexiform Tumor Burden in Patients With Neurofibromatosis-Type 1

Enrolling by invitation

200 enrolled

Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02777775 2025-07-24

Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.

71 enrolled

CNSDermatologic

Neurofibromatosis 1, Skin Neoplasms, Neurofibroma, Plexiform

NCT05683678 2025-04-04

US Selumetinib Registry

Terminated

37 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT06379230 2024-04-23

A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE)

Unknown

2,000 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT01800032 2021-05-12

PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)

30 enrolled

CNSGastrointestinalMyeloid

Neurofibroma, Plexiform, Optic Nerve Glioma

NCT03027401 2020-10-08

Clinical Sequencing of Cancer and Tissue Repository: OncoGenomics

Withdrawn

Myelodysplastic Syndromes, Neoplasms, Adenomatous Polyposis Coli, Neurofibroma, Plexiform

NCT00006435 2020-05-04

Study of Plexiform Neurofibromas in Neurofibromatosis Type 1

24 enrolled

Neurofibroma, Plexiform

NCT00340522 2019-12-16

Childhood Cancer and Plexiform Neurofibroma Tissue Microarray for Molecular Target Screening and Clinical Drug Development