Announcements Trials
Browse Landscape

Phase

Phase 2 1

Status

Recruiting 5Active not recruiting 4Completed 3Enrolling by invitation 2

Sponsor Class

INDUSTRY 2OTHER 1NIH 1

Study Type

Observational 3Interventional 1

Sponsor

Cancer Type

CNS 4Sarcoma 1

Conditions

Breast Neoplasms 672Carcinoma, Non-Small-Cell Lung 461Prostatic Neoplasms 390Neoplasms 382Lung Neoplasms 266Multiple Myeloma 246Colorectal Neoplasms 235Neoplasm Metastasis 217Melanoma 203Ovarian Neoplasms 166Leukemia, Myeloid, Acute 166Pancreatic Neoplasms 155Squamous Cell Carcinoma of Head and Neck 141Carcinoma, Renal Cell 141Lymphoma 137Brain Neoplasms 132Leukemia, Lymphocytic, Chronic, B-Cell 126Glioblastoma 126Recurrence 124Lymphoma, Non-Hodgkin 123Carcinoma, Hepatocellular 119Head and Neck Neoplasms 115Urinary Bladder Neoplasms 111Triple Negative Breast Neoplasms 110Stomach Neoplasms 110Precursor Cell Lymphoblastic Leukemia-Lymphoma 105Uterine Cervical Neoplasms 102Hematologic Neoplasms 100Lymphoma, Follicular 96Sarcoma 95

Interventions

mirdametinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Active not recruiting × Neurofibroma × 1 year × Clear all
NCT00924196 2026-06-04

Natural History Study of Patients With Neurofibromatosis Type I

National Institutes of Health Clinical Center (CC)

Active not recruiting
259 enrolled
CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform, Neurofibrosarcoma, Optic Nerve Glioma

NCT03962543 2026-05-06

ReNeu

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Phase 2 Active not recruiting
114 enrolled 25 charts 1 FDA
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT05581511 2025-10-14

cNF Natural Hx

Johns Hopkins University

Active not recruiting
500 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT05891847 2025-06-10

Non-interventional Study of Patients With PN NF1 Starting Selumetinib in Russia

AstraZeneca

Active not recruiting
150 enrolled
CNS

Neurofibroma

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