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Phase 1 1

Status

Recruiting 1

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OTHER 1

Study Type

Interventional 1

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Cancer Type

CNS 1

Conditions

Melanoma 20Sarcoma 8Breast Neoplasms 5Carcinoma, Merkel Cell 4Triple Negative Breast Neoplasms 3Neoplasm Metastasis 3Carcinoma, Squamous Cell 3Pancreatic Neoplasms 2Mycosis Fungoides 2Lymphoma, T-Cell, Cutaneous 2Carcinoma, Basal Cell 2Squamous Cell Carcinoma of Head and Neck 1Skin Neoplasms 1Sezary Syndrome 1Sarcoma, Kaposi 1Recurrence 1Rectal Neoplasms 1Pleural Effusion, Malignant 1Peritoneal Neoplasms 1Paget Disease, Extramammary 1Neurofibromatosis 1 1Neurofibromatoses 1Neurofibroma 1Muir-Torre Syndrome 1Microcystic adnexal carcinoma 1Lymphoma, T-Cell 1Lymphoma, Large-Cell, Anaplastic 1Lung Neoplasms 1Liposarcoma 1Leiomyosarcoma 1

Interventions

mirdametinib 2tipifarnib 1talimogene laherparepvec 1peginterferon alfa-2b 1nilotinib 1binimetinib 1antineoplaston AS 2-1 1antineoplaston A10 1Vincristine 1Temozolomide 1Talaporfin 1Sirolimus 1Restraint, Physical 1Ranibizumab 1Radiosurgery 1Photochemotherapy 1Neurofibromin 1 1Mn-PyC3A 1Imatinib Mesylate 1Everolimus 1Elasticity Imaging Techniques 1Deoxycholic Acid 1Cryotherapy 1Celecoxib 1Aminolevulinic Acid 1

Date Range

30 days90 days1 yearAll

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Clinical Trials

1 trials
RecentStart dateEnrollment
Interventional × Neurofibroma × talimogene laherparepvec × Clear all
NCT07102394 2026-05-08

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Johns Hopkins University

Phase 1 Recruiting
10 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

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