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Phase

Phase 2 6Phase NA 5Phase 1 4Phase EARLY_PHASE1 2Phase 1/2 1

Status

Terminated 1Recruiting 1Enrolling by invitation 1Completed 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Breast Neoplasms 523Leukemia, Myeloid, Acute 499Neoplasms 381Carcinoma, Non-Small-Cell Lung 381Pancreatic Neoplasms 329Precursor Cell Lymphoblastic Leukemia-Lymphoma 319Multiple Myeloma 312Glioblastoma 311Melanoma 309Prostatic Neoplasms 293Leukemia 289Neoplasm Metastasis 284Brain Neoplasms 276Lymphoma 271Lung Neoplasms 270Recurrence 266Ovarian Neoplasms 247Colorectal Neoplasms 246Lymphoma, Non-Hodgkin 242Leukemia, Lymphocytic, Chronic, B-Cell 231Myelodysplastic Syndromes 208Glioma 208Lymphoma, Large B-Cell, Diffuse 186Carcinoma, Hepatocellular 173Lymphoma, Follicular 167Head and Neck Neoplasms 162Hodgkin Disease 160Lymphoma, Mantle-Cell 155Burkitt Lymphoma 154Sarcoma 150

Interventions

talimogene laherparepvec 1Talaporfin 1Sirolimus 1Deoxycholic Acid 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × OTHER × Neurofibroma × Clear all
NCT07102394 2026-05-08

Feasibility and Tolerability of IMLYGIC for the Treatment of Cutaneous Neurofibromas in Adults With NF1

Johns Hopkins University

Phase 1 Recruiting
10 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT06300502 2026-04-22

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Massachusetts General Hospital

Phase 1 Enrolling by invitation
15 enrolled
CNS

Neurofibroma, Neurofibromatosis 1

NCT00716469 2015-04-15

PDT

Children's Hospital of Philadelphia

Phase 1 Terminated
7 enrolled
CNS

Neurofibroma

NCT01031901 2012-02-27

Topical Rapamycin Therapy to Alleviate Cutaneous Manifestations of Tuberous Sclerosis Complex (TSC) and Neurofibromatosis I (NF1)

The University of Texas Health Science Center, Houston

Phase 1 Completed
52 enrolled
CNS

Neurofibroma, Tuberous Sclerosis, Neurofibromatoses, Angiofibroma

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