Announcements Trials
Browse Landscape

Phase

Phase NA 1Phase 2 1

Status

Completed 13Recruiting 7Active not recruiting 5Terminated 2Enrolling by invitation 2Withdrawn 1Unknown 1

Sponsor Class

OTHER 2INDUSTRY 2NIH 1

Study Type

Observational 3Interventional 2

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Breast Neoplasms 849Carcinoma, Non-Small-Cell Lung 551Neoplasms 509Prostatic Neoplasms 501Lung Neoplasms 313Colorectal Neoplasms 307Multiple Myeloma 289Neoplasm Metastasis 251Melanoma 241Ovarian Neoplasms 215Leukemia, Myeloid, Acute 209Pancreatic Neoplasms 206Squamous Cell Carcinoma of Head and Neck 173Carcinoma, Renal Cell 164Stomach Neoplasms 162Recurrence 161Carcinoma, Hepatocellular 160Lymphoma 156Brain Neoplasms 151Glioblastoma 147Uterine Cervical Neoplasms 144Head and Neck Neoplasms 141Lymphoma, Non-Hodgkin 140Triple Negative Breast Neoplasms 136Leukemia, Lymphocytic, Chronic, B-Cell 136Urinary Bladder Neoplasms 135Precursor Cell Lymphoblastic Leukemia-Lymphoma 132Colonic Neoplasms 115Hematologic Neoplasms 114Lymphoma, Follicular 112

Interventions

mirdametinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Active not recruiting × Neurofibroma × Clear all
NCT00924196 2026-06-04

Natural History Study of Patients With Neurofibromatosis Type I

National Institutes of Health Clinical Center (CC)

Active not recruiting
259 enrolled
CNSSarcoma

Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform, Neurofibrosarcoma, Optic Nerve Glioma

NCT03962543 2026-05-06

ReNeu

Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany

Phase 2 Active not recruiting
114 enrolled 25 charts 1 FDA
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT05581511 2025-10-14

cNF Natural Hx

Johns Hopkins University

Active not recruiting
500 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT05891847 2025-06-10

Non-interventional Study of Patients With PN NF1 Starting Selumetinib in Russia

AstraZeneca

Active not recruiting
150 enrolled
CNS

Neurofibroma

NCT03820778 2021-03-02

Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1

Children's National Research Institute

Phase NA Active not recruiting
10 enrolled
CNS

Neurofibromatosis, type 4, of Riccardi, Neurofibroma, Neurofibromatosis 1, Neurofibroma, Plexiform

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