Announcements Trials
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Phase

Phase 2 2

Status

Recruiting 8Active not recruiting 5Completed 4Terminated 1Suspended 1

Sponsor Class

OTHER 2NIH 2

Study Type

Observational 2Interventional 2

Sponsor

Cancer Type

CNS 4Sarcoma 1

Conditions

Breast Neoplasms 51Neoplasms 45Colorectal Neoplasms 27Carcinoma, Non-Small-Cell Lung 22Prostatic Neoplasms 20Lung Neoplasms 16Leukemia, Myeloid, Acute 16Recurrence 12Multiple Myeloma 11Melanoma 11Stomach Neoplasms 10Head and Neck Neoplasms 10Ovarian Neoplasms 9Uterine Cervical Neoplasms 8Squamous Cell Carcinoma of Head and Neck 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Lymphoma, Non-Hodgkin 8Pancreatic Neoplasms 7Neoplasm Metastasis 7Myelodysplastic Syndromes 7Lymphoma 7Glioma 7Carcinoma, Renal Cell 7Brain Neoplasms 7Motor Activity 6Leukemia 6Hodgkin Disease 6Esophageal Neoplasms 6Colonic Neoplasms 6Carcinoma, Hepatocellular 6

Interventions

Sirolimus 1N-monoacetylcystine 1Inhalation 1Acetylcysteine 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Completed × Neurofibromatosis 1 × 30 days × Clear all
NCT00111384 2026-06-05

Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)

National Institutes of Health Clinical Center (CC)

Completed
313 enrolled
CNS

Legius syndrome, Neurofibroma, Neurofibromatosis 1

NCT00314119 2026-06-05

Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

National Institutes of Health Clinical Center (CC)

Completed
17 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT04481048 2026-06-05

DoDNAC

Children's Hospital Medical Center, Cincinnati

Phase 2 Completed
25 enrolled 12 charts
CNS

Attention Deficit Disorder with Hyperactivity, Neurofibromatosis 1

NCT03433183 2026-05-27

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Sarcoma Alliance for Research through Collaboration

Phase 2 Completed
21 enrolled 12 charts
CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

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