Announcements Trials
Browse Landscape

Phase

Phase 2 3

Status

Recruiting 15Active not recruiting 11Completed 5Not yet recruiting 2Terminated 1Suspended 1Enrolling by invitation 1

Sponsor Class

OTHER 3NIH 2

Study Type

Interventional 3Observational 2

Sponsor

Cancer Type

CNS 5Sarcoma 1

Conditions

Breast Neoplasms 206Neoplasms 191Carcinoma, Non-Small-Cell Lung 91Colorectal Neoplasms 89Prostatic Neoplasms 78Lung Neoplasms 73Multiple Myeloma 49Head and Neck Neoplasms 47Melanoma 46Pancreatic Neoplasms 43Neoplasm Metastasis 42Leukemia, Myeloid, Acute 41Carcinoma, Hepatocellular 40Recurrence 34Brain Neoplasms 34Squamous Cell Carcinoma of Head and Neck 33Ovarian Neoplasms 31Glioblastoma 29Precursor Cell Lymphoblastic Leukemia-Lymphoma 28Glioma 27Uterine Cervical Neoplasms 26Sarcoma 26Lymphoma, Non-Hodgkin 26Lymphoma 26Stomach Neoplasms 25Lymphoma, Follicular 24Carcinoma, Renal Cell 24Esophageal Neoplasms 22Colonic Neoplasms 22Rectal Neoplasms 21

Interventions

Inhalation 2Acetylcysteine 2Sirolimus 1N-monoacetylcystine 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

5 trials
RecentStart dateEnrollment
Completed × Neurofibromatosis 1 × 90 days × Clear all
NCT00111384 2026-06-05

Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)

National Institutes of Health Clinical Center (CC)

Completed
313 enrolled
CNS

Legius syndrome, Neurofibroma, Neurofibromatosis 1

NCT00314119 2026-06-05

Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

National Institutes of Health Clinical Center (CC)

Completed
17 enrolled
CNS

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT04481048 2026-06-05

DoDNAC

Children's Hospital Medical Center, Cincinnati

Phase 2 Completed
25 enrolled 12 charts
CNS

Attention Deficit Disorder with Hyperactivity, Neurofibromatosis 1

NCT03433183 2026-05-27

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Sarcoma Alliance for Research through Collaboration

Phase 2 Completed
21 enrolled 12 charts
CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT04481035 2026-04-21

NF1NAC

Children's Hospital Medical Center, Cincinnati

Phase 2 Completed
5 enrolled 10 charts
CNS

Neurofibromatosis 1

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