Announcements Trials
Browse Landscape

Phase

Phase 1 4

Status

Completed 3Enrolling by invitation 1

Sponsor Class

OTHER 4

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Neurofibromatosis 1 4Lipoma 2Neurofibroma 1

Interventions

Deoxycholic Acid 4AZD 6244 4Polidocanol 2Lasers, Solid-State 2talimogene laherparepvec 1pomalidomide 1pirfenidone 1lorlatinib 1encorafenib 1diphenylcyclopropenone 1cabozantinib 1binimetinib 1X-Rays 1Vinblastine 1Specimen Handling 1Sorafenib 1Photons 1Pharmacokinetics 1Magnetic Resonance Spectroscopy 1Lovastatin 1Lasers 1Imiquimod 1High-Energy Shock Waves 1Curcumin 1Cetuximab 1Carboplatin 1Biopsy 1Acetaminophen 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 1 × Neurofibromatosis 1 × Deoxycholic Acid × Clear all
NCT06300502 2026-04-22

Assessing the Efficacy of Repeat, Monthly Treatments of Deoxycholate for NF1 Associated Cutaneous Neurofibromas (cNFs)

Massachusetts General Hospital

Phase 1 Enrolling by invitation
15 enrolled
CNS

Neurofibroma, Neurofibromatosis 1

NCT06132165 2025-11-21

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Massachusetts General Hospital

Phase 1 Completed
13 enrolled
CNS

Neurofibromatosis 1

NCT04730583 2025-02-21

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

Massachusetts General Hospital

Phase 1 Completed
34 enrolled
CNS

Neurofibromatosis 1

NCT06120036 2025-02-21

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

Massachusetts General Hospital

Phase 1 Completed
20 enrolled
CNS

Neurofibromatosis 1

Data powered by HemOnc (CC BY 4.0) Colophon âš¡