Announcements Trials
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Phase

Phase 2 2

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Sarcoma 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 32Myelodysplastic Syndromes 30Leukemia, Myeloid, Acute 30Multiple Myeloma 24Lymphoma, Non-Hodgkin 24Hodgkin Disease 24Lymphoma 21Leukemia 21Graft vs Host Disease 21Leukemia, Lymphocytic, Chronic, B-Cell 20Leukemia, Myelogenous, Chronic, BCR-ABL Positive 16Myeloproliferative Disorders 15Lymphoma, Mantle-Cell 15Neoplasms 14Tuberous Sclerosis 13Lymphoma, Large B-Cell, Diffuse 13Hematologic Neoplasms 12Burkitt Lymphoma 12Primary Myelofibrosis 11Lymphoma, Follicular 11Breast Neoplasms 11Waldenstrom Macroglobulinemia 10Sarcoma 10Recurrence 10Neoplasms, Plasma Cell 10Neoplasm Metastasis 10Lymphoma, B-Cell, Marginal Zone 10Leukemia, Myelomonocytic, Chronic 10Prostatic Neoplasms 9Lymphangioleiomyomatosis 9

Interventions

AZD 6244 9Lovastatin 5Deoxycholic Acid 4trametinib 3Lasers, Solid-State 3mirdametinib 2fludarabine 2Transcranial Direct Current Stimulation 2Sirolimus 2Polidocanol 2Magnetic Resonance Imaging 2Lasers 2Lamotrigine 2Inhalation 2Acetylcysteine 2thymoglobulin 1talimogene laherparepvec 1peginterferon alfa-2b 1gadolinium compound P760 1fludarabine phosphate 1diphenylcyclopropenone 1cabozantinib 1binimetinib 1X-Rays 1Vitamin D 1Vincristine 1Vinblastine 1Temozolomide 1Surgical Procedures, Operative 1Sunitinib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
OTHER × Neurofibromatosis 1 × Sirolimus × Clear all
NCT03433183 2026-05-27

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Sarcoma Alliance for Research through Collaboration

Phase 2 Completed
21 enrolled 12 charts
CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT00634270 2017-11-17

Protocol 102

University of Alabama at Birmingham

Phase 2 Completed
58 enrolled 19 charts
CNS

Neurofibromatosis 1

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