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Phase

Phase 2 43Phase NA 32Phase 1 21Phase 1/2 9Phase 3 4Phase 4 2Phase 2/3 2Phase EARLY_PHASE1 1

Status

Active not recruiting 3Completed 1

Sponsor Class

NIH 2INDUSTRY 2

Study Type

Interventional 4

Sponsor

Cancer Type

CNS 4

Conditions

Breast Neoplasms 1128Carcinoma, Non-Small-Cell Lung 718Neoplasms 545Prostatic Neoplasms 502Colorectal Neoplasms 438Multiple Myeloma 336Lung Neoplasms 309Neoplasm Metastasis 288Leukemia, Myeloid, Acute 263Stomach Neoplasms 248Carcinoma, Hepatocellular 245Ovarian Neoplasms 225Rectal Neoplasms 211Colonic Neoplasms 204Lymphoma, Follicular 200Lymphoma 199Leukemia 190Uterine Cervical Neoplasms 181Head and Neck Neoplasms 174Pancreatic Neoplasms 171Lymphoma, Non-Hodgkin 167Leukemia, Lymphocytic, Chronic, B-Cell 166Lymphoma, Large B-Cell, Diffuse 163Recurrence 161Melanoma 158Precursor Cell Lymphoblastic Leukemia-Lymphoma 154Squamous Cell Carcinoma of Head and Neck 147Pain 141Urinary Bladder Neoplasms 139Brain Neoplasms 133

Interventions

Vincristine 1Magnetic Resonance Spectroscopy 1Control Groups 1Carboplatin 1Acceptance and Commitment Therapy 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

4 trials
RecentStart dateEnrollment
Phase 3 × Neurofibromatosis 1 × Clear all
NCT03871257 2026-04-13

A Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromatosis and Low-Grade Glioma

National Cancer Institute (NCI)

Phase 3 Active not recruiting
165 enrolled
CNS

Neurofibromatosis 1

NCT04924608 2026-03-23

KOMET

AstraZeneca

Phase 3 Active not recruiting
145 enrolled 17 charts 1 FDA
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT05913037 2025-03-06

FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform Neurofibromas

Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.

Phase 3 Active not recruiting
167 enrolled
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02471339 2022-06-14

Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain

National Institutes of Health Clinical Center (CC)

Phase 3 Completed
66 enrolled 17 charts
CNS

Neurofibromatosis 1, Neurofibroma, Plexiform

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