Clinical Trials Browser

Completed × NIH × Neurofibromatosis 1 × Clear all

NCT00111384 2026-06-05

Study of Disease Severity in Adults With Neurofibromatosis Type 1 (NF1)

Legius syndrome, Neurofibroma, Neurofibromatosis 1

NCT00314119 2026-06-05

Natural History and Biology of Skin Neurofibromas in Neurofibromatosis Type 1

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses

NCT01553149 2025-01-07

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

Phase 2 Completed

75 enrolled 17 charts

Astrocytoma, Neurofibromatosis 1, Optic Nerve Glioma

NCT04774289 2024-09-19

Incidence of Malignant Peripheral Nerve Sheath Tumor (MPNST) Development in Participants With Neurofibromatosis Type 1 (NF1) Receiving and Not Receiving Medical Therapies Directed at Plexiform Neurofibromas (PN)

Neurofibromatosis 1, Peripheral Nervous System Neoplasms

NCT01445314 2024-08-16

Analysis of Data Collected From Individuals Administered Neurobehavioral Assessments

Behavior, Brain Neoplasms, Neurofibromatosis 1

NCT03531814 2024-06-11

Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials

Phase NA Completed

12 enrolled 18 charts

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT04879160 2024-03-22

Systematically Assessing Changes in Plexiform Neurofibroma Related Disfigurement From Photographs of Subjects With Neurofibromatosis Type 1 on a Phase 2 Clinical Trial

Neurofibromatosis 1

NCT02839720 2023-12-06

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

Phase 2 Completed

11 enrolled 11 charts

Neurofibromatosis 1, Optic Nerve Glioma

NCT02471339 2022-06-14

Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain

Phase 3 Completed

66 enrolled 17 charts

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02415153 2022-04-25

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

Phase 1 Completed

Neurofibromatosis 1, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00026780 2020-10-08

Eligibility Screening for a NCI Pediatric Oncology Branch Research Study

CNSLymphoidOther hematologic neoplasmSarcoma

Neoplasms, Neuroblastoma, Neurofibromatosis 1, Sarcoma, Ewing, Osteosarcoma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00684398 2019-12-16

Adaptation and Quality of Life Among Adults With Neurofibromatosis Type I

Neurofibromatosis 1

NCT00727233 2019-12-12

Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas

Phase 1 Completed

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02153931 2019-01-31

Internet Support Group for Parents of a Child With Neurofibromatosis Type 1

Anxiety Disorders, Depression, Neurofibromatosis 1

NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

Phase 2 Completed

36 enrolled 13 charts

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00021541 2018-04-17

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

Phase 2 Completed

62 enrolled 13 charts

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT00053937 2015-04-30

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas

Phase 1 Completed

CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform