Clinical Trials

228 enrolled

Schwannomatosis, Behavior, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT04941027 2025-12-02

Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1

1,046 enrolled

Neurofibromatosis 1

NCT06132165 2025-11-21

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

13 enrolled

Neurofibromatosis 1

NCT04153344 2025-09-12

NEF-1

30 enrolled

Neurofibromatosis 1

NCT04481035 2025-07-31

NF1NAC

5 enrolled 10 charts

Neurofibromatosis 1

NCT02777775 2025-07-24

Targeting the Mechanisms Underlying Cutaneous Neurofibroma Formation in NF1: A Clinical Translational Approach.

71 enrolled

CNSDermatologic

Neurofibromatosis 1, Skin Neoplasms, Neurofibroma, Plexiform

NCT00624234 2025-07-08

Neurobiology and Treatment of Reading Disability in NF-1

184 enrolled 10 charts

Dyslexia, Learning Disabilities, Neurofibromatosis 1

NCT05912400 2025-05-08

Evaluating Mitochondrial Dysfunction in Patients With Neurofibromatosis Type 1

55 enrolled 19 charts

Neurofibromatosis 1

NCT03231306 2025-05-02

NF108-BINI

45 enrolled 8 charts

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT04561765 2025-03-30

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

122 enrolled 21 charts

Neurofibromatosis 1, Chronic Pain

NCT05196854 2025-02-24

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

54 enrolled

Hypertension, Neurofibromatosis 1, Neurofibromatoses

NCT04730583 2025-02-21

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

34 enrolled

Neurofibromatosis 1

NCT06120036 2025-02-21

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

20 enrolled

Neurofibromatosis 1

NCT01595139 2024-12-06

MicroRNAs in Patients With Neurofibromatosis Type 1

9 enrolled

Glioma, Neurofibromatosis 1

NCT05149469 2024-10-16

NF1

60 enrolled

Neurofibromatosis 1

NCT02700230 2024-09-27

Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

9 enrolled

CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT05438290 2024-05-06

DPCP to Treat Cutaneous Neurofibromas Associated With NF1

17 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT03326388 2024-04-04

INSPECT

Phase 1/2 Completed

14 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform, Optic Nerve Glioma

NCT03433183 2023-12-26

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

21 enrolled

CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT02332902 2023-12-20

DCLNF1

24 enrolled 4 charts

Neurofibroma, Neurofibromatosis 1

NCT05377008 2023-09-22

OPTIMAL-SSI

38 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT00846430 2023-08-30

Medical Treatment of "High-Risk" Neurofibromas

9 enrolled 9 charts

Neurofibroma, Neurofibromatosis 1

NCT04212351 2022-08-31

Frameshift Peptides of Children With NF1

60 enrolled

Neurofibromatosis 1

NCT02944032 2022-03-03

COGTRAIN

103 enrolled

Neurofibromatosis 1

NCT04991428 2021-08-05

Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1

31 enrolled

Neurofibromatosis 1

NCT03826940 2021-04-02

ASD/NF1inhib

16 enrolled

Autism Spectrum Disorder, Inhibition, Psychological, Neurofibromatosis 1

NCT01058330 2021-03-23

Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1

36 enrolled

Neurofibromatosis 1

NCT03672838 2021-03-18

A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)

33 enrolled

Neurofibromatosis 1, Neurofibromatosis 2

NCT01125046 2021-01-22

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

50 enrolled 13 charts

Brain Neoplasms, Ependymoma, Meningioma, Neurofibromatosis 1, Neuroma, Acoustic, Neurofibromatosis 2

NCT01776125 2019-11-01

Genetic Evaluation of NF1 and Scoliosis Patients

59 enrolled

Neurofibromatosis 1, Scoliosis

NCT03310996 2019-04-24

tDCS is NF1

16 enrolled

Neurofibromatosis 1

NCT00303368 2019-02-25

NF1TD

395 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT00667836 2019-02-25

Multi-center Project: Spinal Abnormalities in Neurofibromatosis Type1 (NF1) Patients

300 enrolled

Neurofibromatosis 1

NCT02096471 2019-01-10

MEK Inhibitor

19 enrolled 14 charts

Neurofibroma, Neurofibromatosis 1

NCT00304083 2018-09-18

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

48 enrolled 10 charts

CNSSarcoma

Neurofibromatosis 1, Sarcoma, Neurofibrosarcoma

NCT00030264 2018-08-08

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

23 enrolled 9 charts

CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT00844129 2018-05-03

Spine

112 enrolled

Neurofibromatosis 1, Scoliosis

NCT00853580 2018-03-12

STARS

146 enrolled 29 charts

Neurofibromatosis 1

NCT00634270 2017-11-17

Protocol 102

58 enrolled 19 charts

Neurofibromatosis 1

NCT03090971 2017-10-26

Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1

7 enrolled

Neurofibromatosis 1

NCT03298438 2017-10-02

NF1

31 enrolled

Neurofibromatosis 1, Stress Disorders, Post-Traumatic

NCT01410006 2017-07-25

NPRI

2,391 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT01707836 2017-05-09

Neurofibromatosis Type 1 Brain Tumor Genetic Risk

176 enrolled

Neurofibromatosis 1

NCT00865644 2017-01-10

Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1

11 enrolled

Neurofibromatosis 1

NCT00352599 2016-11-22

NF1

44 enrolled

Phase EARLY_PHASE1 Completed

Neurofibromatosis 1

NCT00657202 2016-07-07

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

11 enrolled

Neurofibroma, Neurofibromatosis 1

NCT01851135 2016-07-06

NF1-QDV

286 enrolled

Neurofibromatosis 1

NCT02298270 2016-06-23

Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype

65 enrolled

Schwannomatosis, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT00589784 2016-01-25

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

50 enrolled 6 charts