Clinical Trials

21 enrolled 12 charts

CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT04481035 2026-04-21

NF1NAC

5 enrolled 10 charts

Neurofibromatosis 1

NCT05005845 2026-02-17

NFX-179 Topical Gel Treatment for Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

199 enrolled 15 charts

Neurofibromatosis 1

NCT03406208 2025-12-24

Resiliency Training for Adults With Neurofibromatosis Via Live Videoconferencing

228 enrolled

Schwannomatosis, Behavior, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT06132165 2025-11-21

Efficacy of Skin Cooling in Reducing Pain Associated With Non-invasive Treatments of Neurofibromatosis Type 1 Cutaneous Neurofibromas

13 enrolled

Neurofibromatosis 1

NCT00624234 2025-07-08

Neurobiology and Treatment of Reading Disability in NF-1

184 enrolled 10 charts

Dyslexia, Learning Disabilities, Neurofibromatosis 1

NCT03231306 2025-05-02

NF108-BINI

45 enrolled 8 charts

Neurofibroma, Neurofibromatosis 1, Peripheral Nervous System Neoplasms, Neurofibromatoses, Neurofibroma, Plexiform

NCT04561765 2025-03-30

Innovation in the Treatment of Persistent Pain in Adults With NF1: Implementation of the iCanCope Mobile Application- Clinical Trial

122 enrolled 21 charts

Neurofibromatosis 1, Chronic Pain

NCT05196854 2025-02-24

Clinical Hypnosis and Home Blood Pressure Monitoring in Children With Neurofibromatosis Type 1

54 enrolled

Hypertension, Neurofibromatosis 1, Neurofibromatoses

NCT04730583 2025-02-21

Tolerability of Device Based Therapies for Neurofibromatosis Type 1 Cutaneous Neurofibromas

34 enrolled

Neurofibromatosis 1

NCT06120036 2025-02-21

Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas

20 enrolled

Neurofibromatosis 1

NCT01553149 2025-01-07

Low-Dose or High-Dose Lenalidomide in Treating Younger Patients With Recurrent, Refractory, or Progressive Pilocytic Astrocytoma or Optic Pathway Glioma

75 enrolled 17 charts

Astrocytoma, Neurofibromatosis 1, Optic Nerve Glioma

NCT02700230 2024-09-27

Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery

9 enrolled

CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT03531814 2024-06-11

Medication Adherence in Children, Adolescents and Adults With Neurofibromatosis Type 1(NF1) on Clinical Treatment Trials

12 enrolled 18 charts

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT05438290 2024-05-06

DPCP to Treat Cutaneous Neurofibromas Associated With NF1

17 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT03326388 2024-04-04

INSPECT

Phase 1/2 Completed

14 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform, Optic Nerve Glioma

NCT02332902 2023-12-20

DCLNF1

24 enrolled 4 charts

Neurofibroma, Neurofibromatosis 1

NCT02839720 2023-12-06

Selumetinib in Treating Patients With Neurofibromatosis Type 1 and Cutaneous Neurofibroma

11 enrolled 11 charts

Neurofibromatosis 1, Optic Nerve Glioma

NCT05377008 2023-09-22

OPTIMAL-SSI

38 enrolled

Neurofibromatosis 1, Neurofibromatoses

NCT00846430 2023-08-30

Medical Treatment of "High-Risk" Neurofibromas

9 enrolled 9 charts

Neurofibroma, Neurofibromatosis 1

NCT04495127 2023-04-26

Selumetinib Paediatric NF1 Japan Study

12 enrolled

Neurofibromatosis 1

NCT04435665 2022-08-09

NFX-179 Topical Gel Treatment in Adults With Neurofibromatosis 1 (NF1) and Cutaneous Neurofibromas (cNF)

48 enrolled 14 charts

Neurofibromatosis 1

NCT02471339 2022-06-14

Acceptance and Commitment Training for Adolescents and Young Adults With Neurofibromatosis Type 1, Plexiform Neurofibromas, and Chronic Pain

Phase 3 Completed

66 enrolled 17 charts

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT02415153 2022-04-25

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

29 enrolled

Neurofibromatosis 1, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT02944032 2022-03-03

COGTRAIN

103 enrolled

Neurofibromatosis 1

NCT04991428 2021-08-05

Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1

31 enrolled

Neurofibromatosis 1

NCT03826940 2021-04-02

ASD/NF1inhib

16 enrolled

Autism Spectrum Disorder, Inhibition, Psychological, Neurofibromatosis 1

NCT01058330 2021-03-23

Effects of Physical Training on Bone and Muscle Quality, Muscle Strength, and Motor Coordination in Children With NF1

36 enrolled

Neurofibromatosis 1

NCT03672838 2021-03-18

A Single Center Pilot Study to Assess the Intra-observer Reliability of Measuring Muscle Strength Using a Hand Held Dynamometer in Children and Adults With Neurofibromatosis Type 1 (NF1) and Type 2 (NF2)

33 enrolled

Neurofibromatosis 1, Neurofibromatosis 2

NCT03888248 2021-03-16

Whole-body Vibration in Children With Neurofibromatosis Type 1

30 enrolled

Neurofibromatosis 1, Muscle Weakness

NCT01125046 2021-01-22

Bevacizumab in Treating Patients With Recurrent or Progressive Meningiomas

50 enrolled 13 charts

Brain Neoplasms, Ependymoma, Meningioma, Neurofibromatosis 1, Neuroma, Acoustic, Neurofibromatosis 2

NCT00727233 2019-12-12

Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas

9 enrolled

Neurofibromatosis 1, Neurofibroma, Plexiform

NCT03310996 2019-04-24

tDCS is NF1

16 enrolled

Neurofibromatosis 1

NCT02096471 2019-01-10

MEK Inhibitor

19 enrolled 14 charts

Neurofibroma, Neurofibromatosis 1

NCT03649165 2018-11-08

A Study to Evaluate Bioavailability and Food Effect of Selumetinib (AZD6244) in Healthy Male Participants

24 enrolled

Neurofibromatosis 1

NCT00304083 2018-09-18

Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors

48 enrolled 10 charts

CNSSarcoma

Neurofibromatosis 1, Sarcoma, Neurofibrosarcoma

NCT00030264 2018-08-08

Combination Chemotherapy in Treating Patients With Neurofibromatosis and Progressive Plexiform Neurofibromas

23 enrolled 9 charts

CNSOther neoplasm

Neurofibromatosis 1, Precancerous Conditions, Neurofibroma, Plexiform

NCT00076102 2018-04-23

Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform Neurofibromas

36 enrolled 13 charts

Neurofibromatosis 1, Nerve Sheath Neoplasms, Neurofibroma, Plexiform

NCT00021541 2018-04-17

R115777 to Treat Children With Neurofibromatosis Type 1 and Progressive Plexiform Neurofibromas

62 enrolled 13 charts

Neurofibroma, Neurofibromatosis 1, Neurofibromatoses, Neurofibroma, Plexiform

NCT00853580 2018-03-12

STARS

146 enrolled 29 charts

Neurofibromatosis 1

NCT00634270 2017-11-17

Protocol 102

58 enrolled 19 charts

Neurofibromatosis 1

NCT03090971 2017-10-26

Use of Topical Liquid Diclofenac Following Laser Microporation of Cutaneous Neurofibromas in Patients With NF1

7 enrolled

Neurofibromatosis 1

NCT00865644 2017-01-10

Topical Imiquimod 5% Cream for Treatment of Cutaneous Neurofibromas in Adults With Neurofibromatosis 1

11 enrolled

Neurofibromatosis 1

NCT00352599 2016-11-22

NF1

44 enrolled

Phase EARLY_PHASE1 Completed

Neurofibromatosis 1

NCT00657202 2016-07-07

Ranibizumab for Neurofibromas Associated With Neurofibromatosis 1

11 enrolled

Neurofibroma, Neurofibromatosis 1

NCT01851135 2016-07-06

NF1-QDV

286 enrolled

Neurofibromatosis 1

NCT02298270 2016-06-23

Resiliency Training for Patients With Neurofibromatosis Via Videoconferencing With Skype

65 enrolled

Schwannomatosis, Neurofibromatosis 1, Neurofibromatosis 2, Neurofibromatoses

NCT00589784 2016-01-25

Phase II Trial of Sunitinib (SU011248) in Patients With Recurrent or Inoperable Meningioma

50 enrolled 6 charts

Brain Neoplasms, Meningioma, Neurofibromatosis 1, Neurofibromatosis 2, Central Nervous System Neoplasms, Neurofibromatoses, Hemangioblastoma

NCT02422732 2015-08-19

Functional Imaging and Reading Deficit in Children With NF1

25 enrolled

Dyslexia, Neurofibromatosis 1

NCT00053937 2015-04-30

Pirfenidone in Treating Young Patients With Neurofibromatosis Type 1 and Plexiform Neurofibromas