Announcements Trials
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Phase

Phase 1/2 2Phase 2 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 16Lymphoma, Non-Hodgkin 16Myelodysplastic Syndromes 15Leukemia, Myeloid, Acute 15Leukemia, Lymphocytic, Chronic, B-Cell 15Hodgkin Disease 15Lymphoma, Mantle-Cell 14Multiple Myeloma 13Waldenstrom Macroglobulinemia 12Graft vs Host Disease 12Lymphoma, Large B-Cell, Diffuse 11Lymphoma 11Leukemia 11Lymphoma, Follicular 10Lymphoma, B-Cell, Marginal Zone 10Sarcoma 9Myeloproliferative Disorders 9Burkitt Lymphoma 9Tuberous Sclerosis 7Leukemia, Myelogenous, Chronic, BCR-ABL Positive 7Primary Myelofibrosis 6Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 6Neoplasms 6Lymphoma, Large-Cell, Immunoblastic 6Leukemia, Myelomonocytic, Chronic 6Congenital Abnormalities 6Breast Neoplasms 6Myelodysplastic-Myeloproliferative Diseases 5Lymphoma, Large-Cell, Anaplastic 5Lymphangioleiomyomatosis 5

Interventions

pazopanib 4Doxorubicin 4Sirolimus 3Ifosfamide 3Sorafenib 2Radiotherapy 2Etoposide 2thymoglobulin 1temsirolimus 1tazemetostat 1sapanisertib 1romidepsin 1pexidartinib 1lorvotuzumab mertansine 1liposomal doxorubicin 1indolepropanol phosphate 1fludarabine phosphate 1Watchful Waiting 1Thiotepa 1Tacrolimus 1Sunitinib 1Stem Cell Transplantation 1STA 9090 1Razoxane 1Radiotherapy, Intensity-Modulated 1Radiotherapy, Conformal 1Radiation 1Polymerase Chain Reaction 1Observation 1Neoadjuvant Therapy 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Has results × Neurofibrosarcoma × Sirolimus × Clear all
NCT03433183 2026-05-27

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Sarcoma Alliance for Research through Collaboration

Phase 2 Completed
21 enrolled 12 charts
CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT02584647 2025-03-21

PLX3397

Columbia University

Phase 1/2 Terminated
39 enrolled 13 charts
Sarcoma

Sarcoma, Neurofibrosarcoma

NCT02008877 2019-05-15

SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

Sarcoma Alliance for Research through Collaboration

Phase 1/2 Completed
20 enrolled 20 charts
Sarcoma

Sarcoma, Neurofibrosarcoma

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