Announcements Trials
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Phase

Phase 1/2 2Phase 2 1

Status

Completed 2Terminated 1

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 1

Conditions

Precursor Cell Lymphoblastic Leukemia-Lymphoma 32Myelodysplastic Syndromes 30Leukemia, Myeloid, Acute 30Multiple Myeloma 24Lymphoma, Non-Hodgkin 24Hodgkin Disease 24Lymphoma 21Leukemia 21Graft vs Host Disease 21Leukemia, Lymphocytic, Chronic, B-Cell 20Leukemia, Myelogenous, Chronic, BCR-ABL Positive 16Myeloproliferative Disorders 15Lymphoma, Mantle-Cell 15Neoplasms 14Tuberous Sclerosis 13Lymphoma, Large B-Cell, Diffuse 13Hematologic Neoplasms 12Burkitt Lymphoma 12Primary Myelofibrosis 11Lymphoma, Follicular 11Breast Neoplasms 11Waldenstrom Macroglobulinemia 10Sarcoma 10Recurrence 10Neoplasms, Plasma Cell 10Neoplasm Metastasis 10Lymphoma, B-Cell, Marginal Zone 10Leukemia, Myelomonocytic, Chronic 10Prostatic Neoplasms 9Lymphangioleiomyomatosis 9

Interventions

Doxorubicin 6Radiotherapy 5selinexor 4pazopanib 3Sirolimus 3Ifosfamide 3AZD 6244 3pembrolizumab 2fludarabine phosphate 2Radiation Dose Hypofractionation 2Nivolumab 2Etoposide 2thymoglobulin 1temsirolimus 1tazemetostat 1sotigalimab 1ribociclib 1pexidartinib 1pegfilgrastim 1liposomal doxorubicin 1lentiviral minigene vaccine of COVID-19 coronavirus 1ixazomib 1fludarabine 1decitabine and cedazuridine drug combination 1X-Rays 1Thiotepa 1Tacrolimus 1Surgical Procedures, Operative 1Sunitinib 1Stem Cell Transplantation 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
OTHER × Neurofibrosarcoma × Sirolimus × Clear all
NCT03433183 2026-05-27

SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors

Sarcoma Alliance for Research through Collaboration

Phase 2 Completed
21 enrolled 12 charts
CNSSarcoma

Neurofibromatosis 1, Neurofibrosarcoma

NCT02584647 2025-03-21

PLX3397

Columbia University

Phase 1/2 Terminated
39 enrolled 13 charts
Sarcoma

Sarcoma, Neurofibrosarcoma

NCT02008877 2019-05-15

SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)

Sarcoma Alliance for Research through Collaboration

Phase 1/2 Completed
20 enrolled 20 charts
Sarcoma

Sarcoma, Neurofibrosarcoma

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