Transformation of Plexiform Neurofibromas to Malignant Peripheral Nerve Sheath Tumors in Neurofibromatosis Type 1
Phase 1 Completed
10 enrolled
A Study of Different Dosing Schedules of Selinexor in Sarcoma Patients
Phase 1 Completed
56 enrolled
Vaccine Therapy in Treating Patients with Malignant Peripheral Nerve Sheath Tumor That is Recurrent or Cannot Be Removed by Surgery
Phase 1 Completed
9 enrolled
SARC031: MEK Inhibitor Selumetinib (AZD6244) in Combination With the mTOR Inhibitor Sirolimus for Patients With Malignant Peripheral Nerve Sheath Tumors
Phase 2 Completed
21 enrolled
Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma
Phase 2 Completed
73 enrolled 11 charts
Ribociclib and Doxorubicin in Treating Patients With Metastatic or Advanced Soft Tissue Sarcomas That Cannot Be Removed by Surgery
Phase 1 Completed
16 enrolled
Perifosine in Treating Patients With Metastatic or Locally Advanced Soft Tissue Sarcoma
Phase 2 Completed
17 enrolled
PET CT as Predictor of Response in Preoperative Chemotherapy for Soft Tissue Sarcoma
Phase NA Completed
70 enrolled
Observation, Radiation Therapy, Combination Chemotherapy, and/or Surgery in Treating Young Patients With Soft Tissue Sarcoma
Phase 3 Completed
588 enrolled 22 charts
Lorvotuzumab Mertansine in Treating Younger Patients With Relapsed or Refractory Wilms Tumor, Rhabdomyosarcoma, Neuroblastoma, Pleuropulmonary Blastoma, Malignant Peripheral Nerve Sheath Tumor, or Synovial Sarcoma
Phase 2 Completed
62 enrolled 15 charts
Gemcitabine With or Without Pazopanib in Treating Patients With Refractory Soft Tissue Sarcoma
Phase 2 Completed
54 enrolled 12 charts
VORTEX
Phase 3 Completed
216 enrolled
Comparison of Filgrastim and Filgrastim SD/01in Boosting White Cell Counts After Intensive Chemotherapy
Phase 1 Completed
34 enrolled
SARC023: Ganetespib and Sirolimus in Patients With MPNST (Malignant Peripheral Nerve Sheath Tumors)
Phase 1/2 Completed
20 enrolled 20 charts
Safety and Efficacy Study of Torisel and Liposomal Doxorubicin for Patients With Recurrent Sarcoma
Phase 1/2 Completed
24 enrolled 14 charts
SARC016: Study of Everolimus With Bevacizumab to Treat Refractory Malignant Peripheral Nerve Sheath Tumors
Phase 2 Completed
25 enrolled 15 charts
Trial of Dasatinib in Advanced Sarcomas
Phase 2 Completed
366 enrolled 16 charts
Combination Chemotherapy in Treating Patients With Stage III or Stage IV Malignant Peripheral Nerve Sheath Tumors
Phase 2 Completed
48 enrolled 10 charts
Vismodegib and Gamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Advanced or Metastatic Sarcoma
Phase 1/2 Completed
78 enrolled 11 charts
HSV1716 in Patients With Non-Central Nervous System (Non-CNS) Solid Tumors
Phase 1 Completed
18 enrolled
Alisertib in Treating Patients With Advanced or Metastatic Sarcoma
Phase 2 Completed
72 enrolled 13 charts
S0330 Erlotinib in Treating Patients With Unresectable or Metastatic Malignant Peripheral Nerve Sheath Tumor
Phase 2 Completed
24 enrolled 7 charts
Depsipeptide (Romidepsin) in Treating Patients With Metastatic or Unresectable Soft Tissue Sarcoma
Phase 2 Completed
40 enrolled 11 charts
Celecoxib and Radiation Therapy in Treating Patients With Stage II or Stage III Soft Tissue Sarcoma of the Arm, Hand, Leg, or Foot That Has Been Removed by Surgery
Phase 1 Completed
3 enrolled
Phase II Study of Imatinib Mesylate in Patients With Life Threatening Malignant Rare Diseases
Phase 2 Completed
185 enrolled
Surgery With or Without Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Retroperitoneum or Pelvis
Phase 3 Completed
370 enrolled
Cixutumumab and Doxorubicin Hydrochloride in Treating Patients With Unresectable, Locally Advanced, or Metastatic Soft Tissue Sarcoma
Phase 1 Completed
30 enrolled
Safety Study of Recombinant Vaccinia Virus to Treat Refractory Solid Tumors in Pediatric Patients
Phase 1 Completed
6 enrolled
Sunitinib in Treating Patients With Metastatic, Locally Advanced, or Locally Recurrent Sarcomas
Phase 2 Completed
53 enrolled 6 charts
Sorafenib and Dacarbazine in Soft Tissue Sarcoma
Phase 2 Completed
37 enrolled 6 charts
Doxorubicin With or Without Ifosfamide and Pegfilgrastim in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma
Phase 3 Completed
455 enrolled
Surgery With or Without Chemotherapy in Treating Patients With Soft Tissue Sarcoma
Phase 3 Completed
350 enrolled
Sorafenib in Treating Patients With Metastatic, Locally Advanced, or Recurrent Sarcoma
Phase 2 Completed
147 enrolled 13 charts
BI 2536 in Treating Patients With Recurrent or Metastatic Solid Tumors
Phase 2 Completed
76 enrolled
Combination Chemotherapy With or Without Hyperthermia Therapy in Treating Patients With Soft Tissue Sarcoma
Phase 3 Completed
340 enrolled
Ecteinascidin 743 in Treating Patients With Advanced Soft Tissue Sarcoma
Phase 2 Completed
132 enrolled
STI571 in Treating Patients With Recurrent or Refractory Soft Tissue Sarcoma
Phase 1/2 Completed
91 enrolled
Liposomal Doxorubicin Plus Ifosfamide in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma
Phase 1 Completed
28 enrolled
Exatecan Mesylate in Treating Patients With Advanced Soft Tissue Sarcoma
Phase 2 Completed
39 enrolled
Brostallicin in Treating Patients With Locally Advanced or Metastatic Soft Tissue Sarcoma
Phase 2 Completed
64 enrolled
Surgery With or Without Combination Chemotherapy in Treating Patients With Lung Metastases From Soft Tissue Sarcoma
Phase 3 Completed
340 enrolled
Ifosfamide or Doxorubicin in Treating Patients With Advanced or Metastatic Soft Tissue Sarcoma
Phase 3 Completed
780 enrolled