Clinical Trials Browser

Phase 3 × Completed × Neurotoxicity Syndromes × Clear all

NCT07320950 2026-01-06

Neuroprotective Effect of Neurotropin on Chronic OXA-induced Neurotoxicity in Stage II and Stage III CRC Patients

Phase 3 Completed

Gastrointestinal

Colorectal Neoplasms, Neurotoxicity Syndromes

NCT01099449 2022-11-03

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

Phase 3 Completed

362 enrolled 17 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

Phase 3 Completed

194 enrolled 11 charts

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT00039780 2022-07-13

Evaluation of BNP7787 for the Prevention of Neurotoxicity in Metastatic Breast Cancer Patients Receiving Weekly Paclitaxel

Phase 3 Completed

Breast Diseases, Breast Neoplasms, Neoplasm Metastasis, Neoplasms, Paresthesia, Neurotoxicity Syndromes

NCT00369564 2021-08-11

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

Phase 3 Completed

250 enrolled 10 charts

GenitourinaryLymphoidOther hematologic neoplasmSarcoma

Burkitt Lymphoma, Kidney Neoplasms, Leukemia, Lymphoma, Wilms Tumor, Peripheral Nervous System Diseases, Sarcoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Dendritic Cell Sarcoma, Interdigitating

NCT00068445 2018-05-04

Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Phase 3 Completed

131 enrolled 14 charts

Pain, Neurotoxicity Syndromes

NCT02486198 2018-02-05

Monosialotetrahexosylganglioside for Treatment of Oxaliplatin Induced Neurotoxicity in Gastrointestinal Cancer

Phase 3 Completed

Gastrointestinal

Gastrointestinal Neoplasms, Neurotoxicity Syndromes

NCT00516503 2017-08-24

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Phase 3 Completed

208 enrolled 12 charts

LymphoidMyeloidOther hematologic neoplasmPlasma cell

Leukemia, Lymphoma, Lymphoproliferative Disorders, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Pain, Neurotoxicity Syndromes, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases

NCT00566852 2017-08-21

Memantine in Preventing Side Effects in Patients Undergoing Whole-Brain Radiation Therapy for Brain Metastases From Solid Tumors

Phase 3 Completed

554 enrolled 12 charts

Brain Neoplasms, Neoplasm Metastasis, Neurotoxicity Syndromes

NCT00775645 2017-08-14

S0715: Acetyl-L-Carnitine in Preventing Neuropathy in Women With Stage I, II, or IIIA Breast Cancer Undergoing Chemo

Phase 3 Completed

437 enrolled 14 charts

Breast Neoplasms, Fatigue, Neurotoxicity Syndromes

NCT00489411 2017-04-26

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

Phase 3 Completed

231 enrolled 14 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT02311907 2017-02-23

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

Phase 3 Completed

195 enrolled 12 charts

Fallopian Tube Neoplasms, Ovarian Neoplasms, Pain, Neurotoxicity Syndromes

NCT00316914 2016-08-11

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery

Phase 3 Completed

104 enrolled 15 charts

Gastrointestinal

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00046891 2016-07-06

EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer

Phase 3 Completed

226 enrolled 12 charts

Breast Neoplasms, Neurotoxicity Syndromes

NCT00363129 2016-07-06

Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer

Phase 3 Completed

207 enrolled 13 charts

Neurotoxicity Syndromes

NCT00027963 2016-07-04

Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy

Phase 3 Completed

Pain, Neurotoxicity Syndromes

NCT00305188 2016-05-04

Evaluation of the Efficacy of Xaliproden (SR57746A) in Preventing the Neurotoxicity of Oxaliplatin / 5FU/LV Chemotherapy.

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Paresthesia, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00471445 2015-11-09

Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients

Phase 3 Completed

462 enrolled 14 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT00112996 2014-04-08

Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer

Phase 3 Completed

Neurotoxicity Syndromes

NCT00058071 2013-07-09

Amifostine in Treating Peripheral Neuropathy in Patients Who Have Received Chemotherapy for Cancer

Phase 3 Completed

Hydatidiform Mole, Peripheral Nervous System Diseases, Neurotoxicity Syndromes, Gestational Trophoblastic Disease

NCT00272051 2006-09-13

XENOX - Evaluation of the Efficacy of Xaliproden in Reducing the Neurotoxicity of the Oxaliplatin + 5-FU/LV Chemotherapy

Phase 3 Completed

Gastrointestinal

Neoplasm Metastasis, Paresthesia, Colorectal Neoplasms, Neurotoxicity Syndromes