Clinical Trials

Stomach Neoplasms, Neurotoxicity Syndromes

NCT04150913 2025-11-25

A Phase 2 Trial of Anakinra for the Prevention of CAR-T Cell Mediated Neurotoxicity

15 enrolled 17 charts

Lymphoid

Cytokine Release Syndrome, Lymphoma, Non-Hodgkin, Neurotoxicity Syndromes

NCT00727922 2025-11-20

MnDPDP-K04

23 enrolled

Neoplasms, Neurotoxicity Syndromes

NCT04583124 2025-11-18

ATENTO

Phase NA Completed

42 enrolled

Phase 3 Enrolling by invitation

Breast Neoplasms, Neurotoxicity Syndromes

NCT06950190 2025-08-12

(ECCPC)

100 enrolled

Chemotherapy-Related Cognitive Impairment, Neurotoxicity Syndromes, Cognitive Dysfunction

NCT06551051 2024-09-19

ADC-induced Neurotoxicity Treated With Duloxetine

Phase 2 Recruiting

37 enrolled

Neurotoxicity Syndromes

NCT05510596 2024-08-09

MR-ICANS

Phase NA Completed

25 enrolled

Lymphoid

Cytokine Release Syndrome, Lymphoma, B-Cell, Neurotoxicity Syndromes

NCT05798884 2023-04-05

Electro-acupuncture for the Prevention and Treatment of Oxaliplatin-induced Neurotoxicity in Colorectal Cancer Patients

Phase NA Unknown

150 enrolled

Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00660842 2023-03-24

MITO-7

800 enrolled

Gynecologic

Ovarian Neoplasms, Neurotoxicity Syndromes

NCT01099449 2022-11-03

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity in Patients With Colon Cancer or Rectal Cancer Receiving Oxaliplatin-Based Combination Chemotherapy

362 enrolled 17 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT01372774 2022-09-16

Stereotactic Radiosurgery or Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases That Have Been Removed By Surgery

194 enrolled 11 charts

CNS

Brain Neoplasms, Neoplasm Metastasis, Radiation Injuries, Neurotoxicity Syndromes

NCT00792142 2021-08-19

Bortezomib, Thalidomide, and Dexamethasone After Melphalan and Stem Cell Transplant in Treating Patients With Stage I-III Multiple Myeloma

45 enrolled 8 charts

Plasma cell

Multiple Myeloma, Neurotoxicity Syndromes, Neoplasms, Plasma Cell

NCT01381718 2021-08-13

Modafinil in Treating Children With Memory and Attention Problems Caused by Cancer Treatment for a Brain Tumor

112 enrolled 16 charts

CNS

Fatigue, Central Nervous System Neoplasms, Neurotoxicity Syndromes

NCT00369564 2021-08-11

Glutamic Acid in Reducing Nerve Damage Caused by Vincristine in Young Patients With Cancer

GenitourinaryLymphoidOther hematologic neoplasmSarcoma

250 enrolled 10 charts

Burkitt Lymphoma, Kidney Neoplasms, Leukemia, Lymphoma, Wilms Tumor, Peripheral Nervous System Diseases, Sarcoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Dendritic Cell Sarcoma, Interdigitating

NCT00452868 2018-09-07

Donepezil in Treating Young Patients With Primary Brain Tumors Previously Treated With Radiation Therapy to the Brain

Phase EARLY_PHASE1 Completed

14 enrolled 7 charts

CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Radiation Injuries, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neurotoxicity Syndromes, Optic Nerve Glioma

NCT00068445 2018-05-04

Lamotrigine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

131 enrolled 14 charts

Pain, Neurotoxicity Syndromes

NCT02486198 2018-02-05

Monosialotetrahexosylganglioside for Treatment of Oxaliplatin Induced Neurotoxicity in Gastrointestinal Cancer

145 enrolled

Gastrointestinal Neoplasms, Neurotoxicity Syndromes

NCT01279681 2017-12-08

Combination Chemotherapy Plus Bevacizumab With or Without Oxaliplatin in Treating Older Patients With Metastatic Colorectal Cancer

Phase 3 Terminated

32 enrolled 14 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT01050075 2017-11-06

Acupuncture in Treating Nerve Pain in Patients With Stage I, Stage II, or Stage III Breast Cancer Who Are Receiving Paclitaxel

Phase NA Terminated

7 enrolled

Breast Neoplasms, Breast Neoplasms, Male, Neurotoxicity Syndromes

NCT03330964 2017-11-06

Clinical Trial of Electroacupuncture Stimulation on Prevention and Treatment of Oxaliplatin Neurotoxicity

Phase NA Unknown

120 enrolled

Gastrointestinal Neoplasms, Neurotoxicity Syndromes

NCT00754767 2017-09-11

L-Carnitine L-Tartrate in Preventing Peripheral Neuropathy Caused By Chemotherapy in Women With Metastatic Breast Cancer

Phase 4 Terminated

2 enrolled 3 charts

Breast Neoplasms, Neurotoxicity Syndromes

NCT00516503 2017-08-24

Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

LymphoidMyeloidOther hematologic neoplasmPlasma cell

208 enrolled 12 charts

Leukemia, Lymphoma, Lymphoproliferative Disorders, Multiple Myeloma, Myelodysplastic Syndromes, Myeloproliferative Disorders, Pain, Neurotoxicity Syndromes, Neoplasms, Plasma Cell, Myelodysplastic-Myeloproliferative Diseases

NCT00489411 2017-04-26

Duloxetine in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer

231 enrolled 14 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT00952848 2017-03-29

Electrical Stimulation Therapy Using the MC5-A Scrambler in Reducing Peripheral Neuropathy Caused by Chemotherapy

18 enrolled 10 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT02311907 2017-02-23

Glutathione in Preventing Peripheral Neuropathy Caused by Paclitaxel and Carboplatin in Patients With Ovarian Cancer, Fallopian Tube Cancer, and/or Primary Peritoneal Cancer

195 enrolled 12 charts

Gynecologic

Fallopian Tube Neoplasms, Ovarian Neoplasms, Pain, Neurotoxicity Syndromes

NCT00365768 2016-09-09

Glutamine in Treating Neuropathy Caused by Vincristine in Young Patients With Lymphoma, Leukemia, or Solid Tumors

GenitourinaryLymphoidOther hematologic neoplasmSarcoma

56 enrolled 5 charts

Burkitt Lymphoma, Kidney Neoplasms, Leukemia, Lymphoma, Wilms Tumor, Peripheral Nervous System Diseases, Sarcoma, Lymphoma, Large B-Cell, Diffuse, Neuroectodermal Tumors, Primitive, Peripheral, Neurotoxicity Syndromes, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT00316914 2016-08-11

Calcium Gluconate and Magnesium Sulfate in Preventing Neurotoxicity Caused By Oxaliplatin in Patients Receiving Combination Chemotherapy for Stage II, Stage III, or Stage IV Colorectal Cancer That Has Been Completely Removed By Surgery

104 enrolled 15 charts

Colonic Neoplasms, Rectal Neoplasms, Colorectal Neoplasms, Neurotoxicity Syndromes

NCT00046891 2016-07-06

EGb761 in Maintaining Mental Clarity in Women Receiving Chemotherapy for Newly Diagnosed Breast Cancer

226 enrolled 12 charts

Breast Neoplasms, Neurotoxicity Syndromes

NCT00363129 2016-07-06

Vitamin E in Preventing Peripheral Neuropathy Caused by Chemotherapy in Patients Receiving Chemotherapy for Cancer

207 enrolled 13 charts

Neurotoxicity Syndromes

NCT00027963 2016-07-04

Gabapentin in Treating Peripheral Neuropathy in Cancer Patients Undergoing Chemotherapy

100 enrolled

Pain, Neurotoxicity Syndromes

NCT01882621 2016-06-01

Monosialoganglioside(GM1) Preventing Neurotoxicity Induced by Cisplatin Contained Chemotherapy in NSCLC Patients

300 enrolled

Thoracic

Carcinoma, Non-Small-Cell Lung, Neurotoxicity Syndromes

NCT00471445 2015-11-09

Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients

462 enrolled 14 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT02024412 2015-09-28

Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in mCRC

240 enrolled

Colorectal Neoplasms, Neurotoxicity Syndromes

NCT02024438 2015-09-28

Monosialotetrahexosylganglioside Sodium Injection for Prevention Neurotoxicity of mFOLFOX 6 in Advanced Gastric Cancer

240 enrolled

Stomach Neoplasms, Neurotoxicity Syndromes

NCT02500810 2015-07-17

Monosialoganglioside Preventing Neurotoxicity Induced by Albumin-bound Paclitaxel Chemotherapy in Lung Cancer Patients

Phase 2 Unknown

106 enrolled

Neurotoxicity Syndromes

NCT00666484 2014-12-04

Combination Chemotherapy in Treating Younger Patients With Hodgkin Lymphoma

47 enrolled

Lymphoid

Hodgkin Disease, Lymphoma, Neurotoxicity Syndromes

NCT00112996 2014-04-08

Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer

244 enrolled

Neurotoxicity Syndromes

NCT00069927 2014-02-03

Adderall XR Compared With Concerta in Treating Young Cancer Patients With Memory, Attention, and Depression

Phase 2 Terminated

12 enrolled

Depression, Neurotoxicity Syndromes

NCT00727831 2014-01-27

Methotrexate, Glucarpidase, and Leucovorin in Treating Patients With Newly Diagnosed Primary Central Nervous System Lymphoma

Phase 1/2 Completed

4 enrolled

LymphoidOther

Lymphoma, Lymphoma, Large B-Cell, Diffuse, Neurotoxicity Syndromes, Mucositis

NCT00301080 2013-12-02

D-cycloserine in the Management of Chemotherapy-Induced Peripheral Neuropathic Pain

Phase 3 Terminated

7 enrolled 3 charts

Breast Neoplasms, Pain, Neurotoxicity Syndromes

NCT01196442 2013-08-23

Electrical Stimulation Pain Therapy in Treating Chronic Pain and Numbness Caused By Chemotherapy in Patients With Cancer

Phase NA Completed

39 enrolled 13 charts

Pain, Peripheral Nervous System Diseases, Neurotoxicity Syndromes

NCT00078845 2012-10-17

Amifostine in Treating Peripheral Neuropathy Caused by Paclitaxel in Patients With Solid Tumors