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Phase

Phase 4 1Phase 2/3 1Phase 1 1

Status

Completed 2Unknown 1

Sponsor Class

OTHER 2NIH 1

Study Type

Interventional 3

Sponsor

Cancer Type

Gastrointestinal 2Other hematologic neoplasm 1Lymphoid 1Dermatologic 1

Conditions

Colorectal Neoplasms 408Rectal Neoplasms 152Colonic Neoplasms 150Pancreatic Neoplasms 112Stomach Neoplasms 110Neoplasm Metastasis 87Neoplasms 74Esophageal Neoplasms 60Small Cell Lung Carcinoma 45Neuroblastoma 42Lung Neoplasms 42Glioblastoma 38Carcinoma, Non-Small-Cell Lung 38Brain Neoplasms 33Esophageal Squamous Cell Carcinoma 32Unspecified Adult Solid Tumor, Protocol Specific 31Glioma 31Breast Neoplasms 28Central Nervous System Neoplasms 27Adenocarcinoma Of Esophagus 27Sarcoma 26Gliosarcoma 22Astrocytoma 22Rhabdomyosarcoma 21Sarcoma, Ewing 18Adenocarcinoma 18Gastrointestinal Neoplasms 17Oligodendroglioma 16Recurrence 14Biliary Tract Neoplasms 14

Interventions

pegfilgrastim 30Filgrastim 29Cyclophosphamide 10pegylated granulocyte colony-stimulating factor 8Docetaxel 8Etoposide 7Cytarabine 7Ciprofloxacin 6Cefepime 6Vancomycin 5Leucovorin 5Fluorouracil 5eflapegrastim 4Granulocyte Colony-Stimulating Factor 4Doxorubicin 4Peripheral Blood Stem Cell Transplantation 3Mitoxantrone 3Methotrexate 3Levofloxacin 3Irinotecan 3Idarubicin 3Daunorubicin 3Cyclosporine 3Caspofungin 3Carboplatin 3Amikacin 3trifluridine tipiracil drug combination 2plerixafor 2liposomal amphotericin B 2Vincristine 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Neutropenia × Irinotecan × Clear all
NCT01271582 2019-01-29

Investigation of Association Between UGT1A1 Polymorphisms and Irinotecan Toxicity in Korean Patients

Asan Medical Center

Phase 4 Unknown
1,500 enrolled
Gastrointestinal

Neutropenia, Stomach Neoplasms, Colorectal Neoplasms

NCT01523431 2017-03-30

Individual Dosage Selection of Irinotecan (CPT-11) Based on UGT1A1 Genotype in Metastatic Colorectal Cancer Patients

The Affiliated Hospital of the Chinese Academy of Military Medical Sciences

Phase 2/3 Completed
583 enrolled
Gastrointestinal

Diarrhea, Neutropenia, Colorectal Neoplasms

NCT00002759 2013-02-05

Irinotecan Plus Cyclosporine and Phenobarbital in Treating Patients With Solid Tumors or Lymphoma

National Cancer Institute (NCI)

Phase 1 Completed
3 enrolled
DermatologicLymphoidOther hematologic neoplasm

Burkitt Lymphoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoma, Follicular, Lymphoma, Non-Hodgkin, Mycosis Fungoides, Neutropenia, Sezary Syndrome, Leukemia, Lymphocytic, Chronic, B-Cell, Lymphoma, Large-Cell, Immunoblastic, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, Large-Cell, Anaplastic, Lymphoma, B-Cell, Marginal Zone, Lymphoma, Mantle-Cell, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Intraocular Lymphoma, Drug-Related Side Effects and Adverse Reactions

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