Announcements Trials
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Phase

Phase 1 2

Status

Completed 2

Sponsor Class

OTHER 1NIH 1

Study Type

Interventional 2

Sponsor

Cancer Type

CNS 2Lymphoid 1

Conditions

Multiple Myeloma 60Lymphoma 56Leukemia, Myeloid, Acute 51Leukemia 50Lymphoma, Non-Hodgkin 48Precursor Cell Lymphoblastic Leukemia-Lymphoma 46Hodgkin Disease 36Myelodysplastic Syndromes 28Lymphoma, Large B-Cell, Diffuse 27Breast Neoplasms 24Lymphoma, Mantle-Cell 23Neuroblastoma 22Leukemia, Lymphocytic, Chronic, B-Cell 22Burkitt Lymphoma 17Lymphoma, Follicular 16Leukemia, Myelogenous, Chronic, BCR-ABL Positive 16Central Nervous System Neoplasms 13Lymphoma, Large-Cell, Immunoblastic 12Sarcoma 11Neoplasms, Plasma Cell 11Brain Neoplasms 11Recurrence 10Lymphoma, B-Cell, Marginal Zone 10Neoplasms 9Hematologic Neoplasms 9Congenital Abnormalities 9Myeloproliferative Disorders 8Leukemia, Myelomonocytic, Chronic 8Leukemia, Biphenotypic, Acute 8Graft vs Host Disease 8

Interventions

Temozolomide 45Radiotherapy 16Carboplatin 15Irinotecan 12Carmustine 12Bevacizumab 12Filgrastim 10Vincristine 9Surgical Procedures, Operative 9Magnetic Resonance Spectroscopy 9Procarbazine 7Peripheral Blood Stem Cell Transplantation 6Imatinib Mesylate 6Erlotinib Hydrochloride 6temsirolimus 5sargramostim 5O(6)-benzylguanine 5Lomustine 5Flucytosine 5Etoposide 5Thiotepa 4Sirolimus 4Cyclophosphamide 4aldesleukin 3Thalidomide 3Surveys and Questionnaires 3Sunitinib 3Radiotherapy, Intensity-Modulated 3Radiation 3Polymerase Chain Reaction 3

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Completed × Oligodendroglioma × Granulocyte Colony-Stimulating Factor × Clear all
NCT03434262 2024-05-31

SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors

St. Jude Children's Research Hospital

Phase 1 Completed
68 enrolled
CNSLymphoid

Choroid Plexus Carcinoma, Microphthalmia, Isolated, with Coloboma 5, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lymphoma, Follicular, Medulloblastoma, Meningioma, Neoplasms, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pinealoma, Recurrence, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Rhabdoid Tumor, Pyloric Stenosis, Hypertrophic

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

National Cancer Institute (NCI)

Phase 1 Completed
72 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

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