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Phase

Phase 1 1

Status

Completed 1

Sponsor Class

OTHER 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1CNS 1

Conditions

Lymphoma 6Lymphoma, Mantle-Cell 3Lymphoma, Large B-Cell, Diffuse 3Lymphoma, Follicular 3Burkitt Lymphoma 3Breast Neoplasms 3Waldenstrom Macroglobulinemia 2Pancreatic Neoplasms 2Lymphoma, T-Cell 2Lymphoma, Large-Cell, Anaplastic 2Lymphoma, B-Cell, Marginal Zone 2Lymphoma, B-Cell 2Leukemia, Lymphocytic, Chronic, B-Cell 2Immunoblastic Lymphadenopathy 2Hodgkin Disease 2Head and Neck Neoplasms 2Gastrointestinal Neoplasms 2Advanced Solid Tumors 2Advanced Nonhematologic Malignancies 2Advanced Malignancies 2Triple Negative Breast Neoplasms 1Small Cell Lung Carcinoma 1Sezary Syndrome 1Recurrence 1Rectal Neoplasms 1Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Oligodendroglioma 1Neuroblastoma 1

Interventions

Temozolomide 27Irinotecan 8Filgrastim 8Carmustine 7Carboplatin 7Surgical Procedures, Operative 6O(6)-benzylguanine 6Flucytosine 6sargramostim 4Vorinostat 42,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 4vocimagene amiretrorepvec 3lonafarnib 3Radiosurgery 3Lenalidomide 3Imatinib Mesylate 3Genetic Therapy 3Erlotinib Hydrochloride 3Cyclophosphamide 3Bortezomib 3temsirolimus 2cediranib 2aldesleukin 2Vincristine 2Vinblastine 2Sirolimus 2Radiotherapy, Intensity-Modulated 2Radiotherapy 2Radiation 2Peripheral Blood Stem Cell Transplantation 2

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Oligodendroglioma × MLN 8237 × Clear all
NCT02186509 2025-04-30

Alisertib and Fractionated Stereotactic Radiosurgery in Treating Patients With Recurrent High Grade Gliomas

Thomas Jefferson University

Phase 1 Completed
17 enrolled 11 charts
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

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