Announcements Trials
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Phase

Phase 1 2Phase 2 1

Status

Completed 3

Sponsor Class

OTHER 3

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3CNS 3

Conditions

Melanoma 134Carcinoma, Renal Cell 51Kidney Neoplasms 42Leukemia, Myeloid, Acute 38Neoplasm Metastasis 37Leukemia 33Lymphoma 30Breast Neoplasms 26Ovarian Neoplasms 24Lymphoma, Non-Hodgkin 22Carcinoma, Non-Small-Cell Lung 22Skin Neoplasms 21Precursor Cell Lymphoblastic Leukemia-Lymphoma 19Neuroblastoma 18Lymphoma, Follicular 18Pancreatic Neoplasms 16Lymphoma, Mantle-Cell 16Leukemia, Lymphocytic, Chronic, B-Cell 16Stomach Neoplasms 14Neoplasms 14Myelodysplastic Syndromes 14Colorectal Neoplasms 13Multiple Myeloma 12Lymphoma, Large B-Cell, Diffuse 12Lymphoma, B-Cell, Marginal Zone 12Hodgkin Disease 12Congenital Abnormalities 12Uterine Cervical Neoplasms 11Lymphoma, Large-Cell, Immunoblastic 11Lung Neoplasms 11

Interventions

Temozolomide 73Radiotherapy 33Carboplatin 21Bevacizumab 18Irinotecan 16Carmustine 16Magnetic Resonance Spectroscopy 15Vincristine 14Surgical Procedures, Operative 13Filgrastim 13Procarbazine 10Erlotinib Hydrochloride 8Cyclophosphamide 8Peripheral Blood Stem Cell Transplantation 7O(6)-benzylguanine 7Lomustine 7Etoposide 7sargramostim 6Imatinib Mesylate 6Flucytosine 6Cisplatin 62-phenyl-6-(2'-(4'-(ethoxycarbonyl)thiazolyl))thiazolo(3,2-b)(1,2,4)triazole 6temsirolimus 5Vorinostat 5Thiotepa 5Radiotherapy, Intensity-Modulated 5Radiation 5Biopsy 52,2-dimethyl-N-(6-oxo-6,7-dihydro-5H-dibenzo(b,d)azepin-7-yl)-N'-(2,2,3,3,3-pentafluoropropyl)malonamide 5vocimagene amiretrorepvec 4

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Interventional × Oligodendroglioma × aldesleukin × Clear all
NCT01082926 2015-06-08

Phase I Study of Cellular Immunotherapy for Recurrent/Refractory Malignant Glioma Using Intratumoral Infusions of GRm13Z40-2, An Allogeneic CD8+ Cytolitic T-Cell Line Genetically Modified to Express the IL 13-Zetakine and HyTK and to be Resistant to Glucocorticoids, in Combination With Interleukin-2

City of Hope Medical Center

Phase 1 Completed
6 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00002572 2013-05-30

Cytotoxic T Cells and Interleukin-2 in Treating Adult Patients With Recurrent Brain Tumors

University of Colorado, Denver

Phase 1 Completed
10 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00004024 2013-04-05

Biological Therapy Following Surgery and Radiation Therapy in Treating Patients With Primary or Recurrent Astrocytoma or Oligodendroglioma

Barbara Ann Karmanos Cancer Institute

Phase 2 Completed
60 enrolled
CNSSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Glioma, Subependymal, Gliosarcoma

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