Clinical Trials

Astrocytoma, Glioma, Oligodendroglioma

NCT05267106 2025-12-30

FIGHT-209

83 enrolled 18 charts

Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms

NCT01849952 2025-09-15

Evaluating the Expression Levels of MicroRNA-10b in Patients With Gliomas

94 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma

NCT06038760 2025-07-30

PEAR-GLIO

12 enrolled

Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Neoplasms, Oligodendroglioma

NCT05297864 2025-05-23

OU-SCC-PI-4G

15 enrolled 13 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT05737212 2025-02-21

Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas

7 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT02372409 2024-11-01

Using MRI-Guided Laser Heat Ablation to Induce Disruption of the Peritumoral Blood Brain Barrier to Enhance Delivery and Efficacy of Treatment of Pediatric Brain Tumors

6 enrolled 10 charts

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Optic Nerve Glioma

NCT02924038 2024-06-14

A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG)

14 enrolled 10 charts

CNSLymphoid

Astrocytoma, Glioma, Lymphoma, Follicular, Oligodendroglioma

NCT02168270 2023-11-24

Temozolomide and Ascorbic Acid in Treating Patients With Recurrent High-Grade Glioma

4 enrolled 6 charts

Astrocytoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT03971734 2023-10-06

Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas

7 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT00788125 2023-07-14

Dasatinib, Ifosfamide, Carboplatin, and Etoposide in Treating Young Patients With Metastatic or Recurrent Malignant Solid Tumors

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

7 enrolled 9 charts

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Burkitt Lymphoma, Carcinoma, Renal Cell, Immunoblastic Lymphadenopathy, Kidney Neoplasms, Liver Neoplasms, Lymphoma, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Recurrence, Sarcoma, Osteosarcoma, Spinal Cord Neoplasms, Teratoma, Testicular Neoplasms, Lymphoma, Large B-Cell, Diffuse, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Nephroma, Mesoblastic, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT01721577 2023-05-22

AXL1717

10 enrolled 8 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01986348 2023-01-26

KING

76 enrolled 16 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT02023905 2022-12-29

Everolimus With and Without Temozolomide in Adult Low Grade Glioma

27 enrolled 15 charts

Astrocytoma, Oligodendroglioma

NCT01884740 2022-08-09

Intraarterial Infusion Of Erbitux and Bevacizumab For Relapsed/Refractory Intracranial Glioma In Patients Under 22

13 enrolled 6 charts

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma

NCT00031798 2021-09-09

Methylphenidate to Improve Quality of Life in Patients Undergoing Radiation Therapy for Brain Tumors

Phase 3 Terminated

Astrocytoma, Brain Neoplasms, Depression, Ependymoma, Fatigue, Glioblastoma, Glioma, Meningioma, Oligodendroglioma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Gliosarcoma

NCT01110876 2021-08-25

Phase I / II Vorinostat, Erlotinib and Temozolomide for Recurrent Glioblastoma Multiforme (GBM)

21 enrolled 8 charts

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02255461 2021-03-02

Palbociclib Isethionate in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

35 enrolled 28 charts

Astrocytoma, Glioblastoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Neoplasms, Neuroepithelial

NCT00756106 2020-05-13

MRI Scans in Evaluating the Effects of Radiation Therapy and Chemotherapy in Patients With Newly Diagnosed Glioblastoma Multiforme or Anaplastic Glioma

15 enrolled 6 charts

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT04327011 2020-03-30

A Continuation Protocol for Patients Previously Enrolled in a Study of Toca 511

65 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01478321 2020-03-12

Efficacy of Hypofractionated XRT w/Bev. + Temozolomide for Recurrent Gliomas

54 enrolled 10 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma

NCT02764151 2020-01-27

First in Patient Study for PF-06840003 in Malignant Gliomas

17 enrolled 35 charts

Astrocytoma, Glioma, Oligodendroglioma

NCT00031538 2019-12-09

Genetic Analysis of Brain Tumors

674 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT00035373 2019-11-07

Eligibility Screening of Patients With Central Nervous System Tumors for the National Cancer Institute s (NCI) Clinical Research Protocols

767 enrolled

Astrocytoma, Neoplasms, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01966809 2019-08-20

Photodynamic Therapy (PDT) For Recurrent High Grade Gliomas

1 enrolled 5 charts

CNSEndocrineSarcoma

Astrocytoma, Brain Neoplasms, Chordoma, Craniopharyngioma, Glioblastoma, Glioma, Meningioma, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pituitary Neoplasms, Germinoma, Optic Nerve Glioma

NCT00243022 2019-04-30

Dietary, Herbal and Alternative Medicine in Glioblastoma Multiforme

12 enrolled 15 charts

Astrocytoma, Brain Edema, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT00671801 2018-11-13

Irinotecan Plus Lenalidomide in Adult Patients With Recurrent Glioblastoma Multiforme: Phase I

24 enrolled

Astrocytoma, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT00631137 2018-08-27

Testosterone Gel in Preventing Weakness Caused by Steroid Therapy in Men With Glioma

1 enrolled 2 charts

Astrocytoma, Glioblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Gliosarcoma

NCT01103375 2018-08-01

Erlotinib Hydrochloride and Isotretinoin in Treating Patients With Recurrent Malignant Glioma

5 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01836549 2018-07-20

Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors

43 enrolled 14 charts

Astrocytoma, Ependymoma, Glioblastoma, Oligodendroglioma, Gliosarcoma, Brain Stem Neoplasms

NCT00471653 2018-07-09

Pharmacokinetics in Patients With Newly Diagnosed High-Grade Glioma Receiving Temozolomide and Radiation Therapy

CNSClassical hematologySarcoma

10 enrolled

Astrocytoma, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Thrombocytopenia, Central Nervous System Neoplasms, Gliosarcoma

NCT01281982 2018-07-05

(11C)dLop as a Marker of P-Glycoprotein Function in Patients With Gliomas

2 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma

NCT01234805 2018-07-03

Yoga Therapy in Treating Patients With Malignant Brain Tumors

9 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00003472 2018-03-21

Antineoplaston Therapy in Treating Patients With Recurrent or Refractory Oligodendroglioma

13 enrolled 6 charts

Oligodendroglioma, Recurrence

NCT01339039 2017-11-17

Plerixafor (AMD3100) and Bevacizumab for Recurrent High-Grade Glioma

26 enrolled

Astrocytoma, Oligodendroglioma

NCT00238173 2017-04-21

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

2 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma, Drug-Related Side Effects and Adverse Reactions

NCT00253721 2017-04-21

Melphalan With BBBD in Treating Patients With Brain Malignancies

Phase EARLY_PHASE1 Terminated

21 enrolled

CNSLymphoid

Astrocytoma, Brain Neoplasms, Glioma, Lymphoma, Medulloblastoma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms

NCT01996527 2017-04-17

3T MRI Biomarkers of Glioma Treatment Response

7 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT02967380 2017-03-27

Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases

14 enrolled

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Multiple Sclerosis, Oligodendroglioma, Pinealoma, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Gliosarcoma

NCT00360828 2017-03-23

Phase II Study of Irinotecan HCI for Recurrent Anaplastic Astrocytomas, Mixed Malignant Gliomas, and Oligodendrogliomas

10 enrolled 6 charts

Astrocytoma, Brain Neoplasms, Glioma, Neurologic Manifestations, Oligodendroglioma

NCT02175745 2017-03-20

18F-FDOPA PET/CT or PET/MRI in Measuring Tumors in Patients With Newly-Diagnosed or Recurrent Gliomas

2 enrolled 7 charts

Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Oligodendroglioma, Neoplasms, Neuroepithelial, Gliosarcoma, Optic Nerve Glioma

NCT01148966 2017-02-15

Aminolevulinic Acid During Surgery in Treating Patients With Malignant Brain Tumors

6 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT02031965 2016-05-30

Oncolytic HSV-1716 in Treating Younger Patients With Refractory or Recurrent High Grade Glioma That Can Be Removed By Surgery

2 enrolled

Astrocytoma, Glioblastoma, Oligodendroglioma, Neoplasms, Neuroepithelial

NCT01189240 2015-12-14

RO4929097and Bevacizumab in Treating Patients With Progressive or Recurrent Malignant Glioma

13 enrolled 13 charts

CNSGastrointestinalGenitourinaryGynecologicLymphoidSarcoma

Astrocytoma, Brain Neoplasms, Glioblastoma, Oligodendroglioma, Gliosarcoma

NCT01132547 2015-07-02

Cyproheptadine in Preventing Weight Loss in Children Receiving Chemotherapy for Cancer

Phase 3 Terminated

22 enrolled 9 charts

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Body Weight Changes, Bone Neoplasms, Cachexia, Chondrosarcoma, Fibrosarcoma, Glioblastoma, Hemangiosarcoma, Liposarcoma, Medulloblastoma, Nausea, Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Sarcoma, Sarcoma, Ewing, Mast-Cell Sarcoma, Osteosarcoma, Testicular Neoplasms, Vomiting, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Hepatoblastoma, Sarcoma, Endometrial Stromal, Neuroectodermal Tumors, Primitive, Peripheral, Neoplasms, Neuroepithelial, Optic Nerve Glioma

NCT01378481 2014-12-23

High-Dose Vorinostat and Fractionated Stereotactic Body Radiation Therapy in Treating Patients With Recurrent Glioma

30 enrolled

Astrocytoma, Brain Neoplasms, Glioblastoma, Glioma, Oligodendroglioma, Gliosarcoma

NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

129 enrolled

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00897377 2014-08-05

Treatment Strategy for Low-grade Gliomas

Phase 3 Terminated

500 enrolled

Astrocytoma, Oligodendroglioma

NCT01095094 2013-06-10

Ritonavir and Lopinavir in Treating Patients With Progressive or Recurrent High-Grade Glioma

19 enrolled 9 charts