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Phase

Phase 1 1

Status

Terminated 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Sarcoma 1Other hematologic neoplasm 1Lymphoid 1Endocrine 1CNS 1

Conditions

Multiple Myeloma 43Precursor Cell Lymphoblastic Leukemia-Lymphoma 14Recurrence 7Lymphoma, Non-Hodgkin 6Burkitt Lymphoma 6Neoplasms, Plasma Cell 5Nausea 5Leukemia 5Vomiting 4Prostatic Neoplasms 4Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 4Neoplasms 4Lymphoma 4Neoplasm Metastasis 3Lymphoma, Large B-Cell, Diffuse 3Hematologic Neoplasms 3Amyloidosis 3Smoldering Multiple Myeloma 2Oligodendroglioma 2Lung Neoplasms 2Leukemia, Myeloid, Acute 2Leukemia, Biphenotypic, Acute 2Immunoglobulin Light-chain Amyloidosis 2Carcinoma, Non-Small-Cell Lung 2Breast Neoplasms 2Astrocytoma 2Waldenstrom Macroglobulinemia 1Uveal Melanoma 1Squamous Cell Carcinoma of Head and Neck 1Spinal Cord Neoplasms 1

Interventions

etoposide phosphate 3Ifosfamide 2Filgrastim 2Etoposide 2Carboplatin 2sodium thiosulfate 1sargramostim 1fluorodopa F 18 1Topotecan 1Thiotepa 1Stem Cell Transplantation 1Semaxinib 1Radiotherapy, Intensity-Modulated 1Radiotherapy 1Perfusion Magnetic Resonance Imaging 1Microarray Analysis 1Mesna 1Melphalan 1Mannitol 1Magnetic Resonance Spectroscopy 1Immunohistochemistry 1Granulocyte Colony-Stimulating Factor 1Dynamic Contrast Enhanced Magnetic Resonance Imaging 1Doxorubicin 1Dexamethasone 1Dasatinib 1Cyproheptadine 1Cyclophosphamide 1Calcium Dobesilate 1Busulfan 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Terminated × Optic Nerve Glioma × Calcium Dobesilate × Clear all
NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

National Cancer Institute (NCI)

Phase 1 Terminated
129 enrolled
CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

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