Announcements Trials
Browse Landscape

Phase

Phase 1 3

Status

Completed 3

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Astrocytoma 9Gliosarcoma 8Glioblastoma 8Central Nervous System Neoplasms 8Oligodendroglioma 6Brain Neoplasms 6Glioma 5Unspecified Adult Solid Tumor, Protocol Specific 3Optic Nerve Glioma 3Medulloblastoma 3Familial ependymoma 3Choroid Plexus Neoplasms 3Lymphoma, Non-Hodgkin 2Ependymoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Sarcoma 1Precursor Cell Lymphoblastic Leukemia-Lymphoma 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroectodermal Tumors, Primitive 1Neuroblastoma 1Lymphoma, T-Cell, Cutaneous 1Lymphoma, Mantle-Cell 1Lymphoma, Large-Cell, Immunoblastic 1Lymphoma, Large B-Cell, Diffuse 1Lymphoma, Follicular 1

Interventions

Filgrastim 8Temozolomide 6Carboplatin 6Granulocyte Colony-Stimulating Factor 4Etoposide 4O(6)-benzylguanine 3Busulfan 3Vorinostat 2Topotecan 2Peripheral Blood Stem Cell Transplantation 2Melphalan 2Irinotecan 2Ifosfamide 2Cyclophosphamide 2veliparib 1trioctyl phosphine oxide 1sodium thiosulfate 1sargramostim 1romidepsin 1pomalidomide 1pazopanib 1lonafarnib 1laromustine 1ixabepilone 1ispinesib 1imetelstat 1exatecan 1etoposide phosphate 1emvododstat 1cediranib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase 1 × Optic Nerve Glioma × O(6)-benzylguanine × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

National Cancer Institute (NCI)

Phase 1 Completed
72 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00003765 2013-02-05

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
36 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

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