Announcements Trials
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Phase

Phase 1 3

Status

Completed 3

Sponsor Class

NIH 3

Study Type

Interventional 3

Sponsor

Cancer Type

CNS 3Sarcoma 1Gynecologic 1Genitourinary 1Gastrointestinal 1

Conditions

Glioblastoma 12Gliosarcoma 11Central Nervous System Neoplasms 10Astrocytoma 10Brain Neoplasms 8Glioma 6Oligodendroglioma 5Optic Nerve Glioma 3Medulloblastoma 3Familial ependymoma 3Choroid Plexus Neoplasms 3Unspecified Adult Solid Tumor, Protocol Specific 2Sarcoma 2Wilms Tumor 1Testicular Neoplasms 1Teratoma 1Sezary Syndrome 1Rectal Neoplasms 1Ovarian Neoplasms 1Ovarian Germ Cell Cancer 1Osteosarcoma 1Neuroectodermal Tumors, Primitive, Peripheral 1Neuroblastoma 1Neoplasms, Plasma Cell 1Mycosis Fungoides 1Multiple Myeloma 1Melanoma 1Lymphoma, T-Cell, Cutaneous 1Liver Neoplasms 1Kidney Neoplasms 1

Interventions

Carboplatin 10Temozolomide 9Filgrastim 7Vincristine 4Irinotecan 4Etoposide 4Radiotherapy 3Peripheral Blood Stem Cell Transplantation 3O(6)-benzylguanine 3Granulocyte Colony-Stimulating Factor 3Vorinostat 2Psychiatric Rehabilitation 2Oxaliplatin 2Lenalidomide 2Cilengitide 2Busulfan 2veliparib 1trioctyl phosphine oxide 1tipifarnib 1romidepsin 1pomalidomide 1pazopanib 1lonafarnib 1laromustine 1ixabepilone 1ispinesib 1imetelstat 1exatecan 1emvododstat 1cediranib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Completed × Optic Nerve Glioma × O(6)-benzylguanine × Clear all
NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

National Cancer Institute (NCI)

Phase 1 Completed
CNSGastrointestinalGenitourinaryGynecologicSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

National Cancer Institute (NCI)

Phase 1 Completed
72 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00003765 2013-02-05

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

National Cancer Institute (NCI)

Phase 1 Completed
36 enrolled
CNS

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

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