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Phase

Phase 1 6Phase 1/2 2Phase EARLY_PHASE1 1Phase 3 1Phase 2 1

Status

Completed 2

Sponsor Class

OTHER 2

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2CNS 2Head & Neck 1Gynecologic 1Genitourinary 1

Conditions

Glioblastoma 69Glioma 26Brain Neoplasms 26Gliosarcoma 23Melanoma 17Central Nervous System Neoplasms 14Astrocytoma 12Neuroblastoma 10Rhabdomyosarcoma 8Small Cell Lung Carcinoma 6Sarcoma, Ewing 6Neoplasms 6Neoplasm Metastasis 6Medulloblastoma 6Recurrence 5Sarcoma 4Ovarian Neoplasms 4Osteosarcoma 4Oligodendroglioma 4Wilms Tumor 3Prostatic Neoplasms 3Neuroectodermal Tumors, Primitive, Peripheral 3Ependymoma 3Diffuse Intrinsic Pontine Glioma 3Breast Neoplasms 3Rhabdoid Tumor 2Pancreatic Neoplasms 2Optic Nerve Glioma 2Lymphoma, Follicular 2Lymphoma 2

Interventions

Temozolomide 2Carboplatin 2etoposide phosphate 1Vincristine 1Radiotherapy 1Peripheral Blood Stem Cell Transplantation 1Microarray Analysis 1Mebendazole 1Irinotecan 1Immunohistochemistry 1Ifosfamide 1Filgrastim 1Dasatinib 1Blotting, Western 1Bevacizumab 1AZD 6244 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1/2 × Optic Nerve Glioma × Temozolomide × Clear all
NCT01837862 2024-07-05

A Phase I Study of Mebendazole for the Treatment of Pediatric Gliomas

Northwell Health

Phase 1/2 Completed
36 enrolled
CNSSarcoma

Diffuse Intrinsic Pontine Glioma, Astrocytoma, Glioblastoma, Glioma, Gliosarcoma, Optic Nerve Glioma

NCT00005952 2013-06-20

Temozolomide Plus Peripheral Stem Cell Transplantation in Treating Children With Newly Diagnosed Malignant Glioma or Recurrent CNS or Other Solid Tumors

Duke University

Phase 1/2 Completed
30 enrolled
CNSGenitourinaryGynecologicHead & NeckSarcoma

Familial ependymoma, Testicular Germ Cell Tumor, Astrocytoma, Head and Neck Neoplasms, Kidney Neoplasms, Medulloblastoma, Nasopharyngeal Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

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