Announcements Trials
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Phase

Phase 1 2

Status

Terminated 1Completed 1

Sponsor Class

OTHER 1NETWORK 1

Study Type

Interventional 2

Sponsor

Cancer Type

Sarcoma 2CNS 2Other hematologic neoplasm 1Lymphoid 1Genitourinary 1

Conditions

Ovarian Neoplasms 21Neoplasms 16Neuroblastoma 14Small Cell Lung Carcinoma 13Carcinoma, Ovarian Epithelial 12Fallopian Tube Neoplasms 11Precursor Cell Lymphoblastic Leukemia-Lymphoma 10Lung Neoplasms 10Recurrence 8Leukemia 8Leukemia, Myeloid, Acute 7Uterine Cervical Neoplasms 6Unspecified Adult Solid Tumor, Protocol Specific 6Neoplasm Metastasis 6Lymphoma 6Sarcoma, Ewing 5Endometrial Neoplasms 5Carcinoma, Non-Small-Cell Lung 5Brain Neoplasms 5Sarcoma 4Lymphoma, Follicular 4Glioma 4Central Nervous System Neoplasms 4Burkitt Lymphoma 4Blast Crisis 4Rhabdomyosarcoma 3Precursor T-Cell Lymphoblastic Leukemia-Lymphoma 3Myelodysplastic Syndromes 3Meningeal Carcinomatosis 3Medulloblastoma 3

Interventions

Filgrastim 8Temozolomide 6Carboplatin 6Granulocyte Colony-Stimulating Factor 4Etoposide 4O(6)-benzylguanine 3Busulfan 3Vorinostat 2Topotecan 2Peripheral Blood Stem Cell Transplantation 2Melphalan 2Irinotecan 2Ifosfamide 2Cyclophosphamide 2veliparib 1trioctyl phosphine oxide 1sodium thiosulfate 1sargramostim 1romidepsin 1pomalidomide 1pazopanib 1lonafarnib 1laromustine 1ixabepilone 1ispinesib 1imetelstat 1exatecan 1etoposide phosphate 1emvododstat 1cediranib 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

2 trials
RecentStart dateEnrollment
Phase 1 × Optic Nerve Glioma × Topotecan × Clear all
NCT00638898 2025-03-20

Busulfan, Melphalan, Topotecan Hydrochloride, and a Stem Cell Transplant in Treating Patients With Newly Diagnosed or Relapsed Solid Tumor

City of Hope Medical Center

Phase 1 Completed
25 enrolled
CNSGenitourinarySarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Testicular Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00112619 2011-06-30

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

Pediatric Brain Tumor Consortium

Phase 1 Terminated
19 enrolled
CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasms, Unknown Primary, Oligodendroglioma, Recurrence, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

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