Clinical Trials

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Bone Neoplasms, Brain Neoplasms, Carcinoma, Renal Cell, Endocrine Gland Neoplasms, Gastrointestinal Neoplasms, Carcinoma, Hepatocellular, Medulloblastoma, Meningioma, Neoplasms, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Pinealoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Urologic Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Muscle Neoplasms, Optic Nerve Glioma, Genetic Diseases, Inborn, Histiocytoma, Malignant Fibrous

NCT00138216 2023-10-02

Temozolomide, Vincristine, and Irinotecan in Treating Young Patients With Refractory Solid Tumors

42 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT02415153 2022-04-25

Pomalidomide in Treating Younger Patients With Recurrent, Progressive, or Refractory Central Nervous System Tumors

29 enrolled

Neurofibromatosis 1, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00007813 2020-02-17

Peripheral Stem Cell Transplantation Plus Chemotherapy in Treating Patients With Malignant Solid Tumors

21 enrolled

Familial ependymoma, Ovarian Germ Cell Cancer, Testicular Germ Cell Tumor, Astrocytoma, Liver Neoplasms, Medulloblastoma, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT01682746 2019-02-25

Photodynamic Therapy (PDT) for Recurrent Pediatric Brain Tumors

5 enrolled

CNSEndocrineSarcoma

Astrocytoma, Brain Neoplasms, Chordoma, Craniopharyngioma, Ependymoma, Glioblastoma, Glioma, Medulloblastoma, Meningioma, Neoplasms, Germ Cell and Embryonal, Oligodendroglioma, Pituitary Neoplasms, Germinoma, Neuroectodermal Tumors, Primitive, Glioma, Subependymal, Optic Nerve Glioma

NCT00623077 2017-12-05

MT2004-30: Tomotherapy for Solid Tumors

CNSGastrointestinalGenitourinaryOther solid neoplasmSarcoma

23 enrolled

Familial ependymoma, Astrocytoma, Carcinoma, Renal Cell, Carcinoma, Hepatocellular, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Retinoblastoma, Sarcoma, Central Nervous System Neoplasms, Hepatoblastoma, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00238173 2017-04-21

Acetylcysteine, Mannitol, Combination Chemotherapy, and Sodium Thiosulfate in Treating Children With Malignant Brain Tumors

2 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma, Drug-Related Side Effects and Adverse Reactions

NCT00326664 2016-03-07

AZD2171 in Treating Young Patients With Recurrent, Progressive, or Refractory Primary CNS Tumors

55 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT01158300 2015-05-04

PTC299 in Treating Young Patients With Refractory or Recurrent Primary Central Nervous System Tumors

28 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Meningioma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00020150 2015-04-29

Temozolomide and O6-benzylguanine in Treating Children With Solid Tumors

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT01088763 2014-11-05

Gamma-Secretase Inhibitor RO4929097 in Treating Young Patients With Relapsed or Refractory Solid Tumors, CNS Tumors, Lymphoma, or T-Cell Leukemia

CNSEndocrineLymphoidOther hematologic neoplasmSarcoma

129 enrolled

Familial ependymoma, Adenoma, Basophil, Adenoma, Chromophobe, Adenoma, Acidophil, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Oligodendroglioma, Pituitary Neoplasms, Recurrence, Spinal Cord Neoplasms, Prolactinoma, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Rhabdoid Tumor, Optic Nerve Glioma, Leukemia, Large Granular Lymphocytic, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Dendritic Cell Sarcoma, Interdigitating

NCT00458744 2014-08-08

Talotrexin in Treating Young Patients With Recurrent Solid Tumors or Leukemia That is Recurrent or Does Not Respond to Treatment

Phase 1 Withdrawn

CNSLymphoidOther hematologic neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Recurrence, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Lymphoma, Extranodal NK-T-Cell, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating

NCT00107458 2014-08-07

Valproic Acid in Treating Young Patients With Recurrent or Refractory Solid Tumors or CNS Tumors

26 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT00003597 2014-07-24

Colony-Stimulating Factors in Treating Children With Recurrent or Refractory Solid Tumors

CNSClassical hematologyDermatologicGenitourinaryGynecologicOther solid neoplasmSarcoma

16 enrolled

Uveal Melanoma, Astrocytoma, Carcinoma, Renal Cell, Medulloblastoma, Melanoma, Neoplasms, Wilms Tumor, Neuroblastoma, Neutropenia, Retinoblastoma, Osteosarcoma, Testicular Neoplasms, Thrombocytopenia, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Gestational Trophoblastic Disease

NCT00946335 2014-07-09

ABT-888 and Temozolomide in Treating Young Patients With Recurrent or Refractory CNS Tumors

31 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00352495 2014-02-13

Vinblastine and Carboplatin in Treating Young Patients With Newly Diagnosed or Recurrent Low-Grade Glioma

26 enrolled

Astrocytoma, Neurofibromatosis 1, Oligodendroglioma, Central Nervous System Neoplasms, Optic Nerve Glioma

NCT01273090 2014-01-30

Imetelstat Sodium in Treating Young Patients With Refractory or Recurrent Solid Tumors or Lymphoma

CNSDermatologicLymphoidSarcoma

34 enrolled

Astrocytoma, Burkitt Lymphoma, Glioblastoma, Hodgkin Disease, Immunoblastic Lymphadenopathy, Lymphoma, Lymphoproliferative Disorders, Mycosis Fungoides, Oligodendroglioma, Recurrence, Sezary Syndrome, Lymphoma, Large B-Cell, Diffuse, Lymphoma, T-Cell, Cutaneous, Lymphoma, T-Cell, Peripheral, Central Nervous System Neoplasms, Lymphoma, Large-Cell, Anaplastic, Neoplasms, Neuroepithelial, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating, Intraocular Lymphoma

NCT00052780 2013-09-30

Temozolomide and O6-Benzylguanine in Treating Children With Recurrent Brain Tumors

72 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00063973 2013-09-30

Cilengitide in Treating Children With Refractory Primary Brain Tumors

24 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00100880 2013-09-30

Lenalidomide in Treating Young Patients With Recurrent, Progressive, or Refractory CNS Tumors

45 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00929903 2013-09-30

Pazopanib Hydrochloride in Treating Young Patients With Solid Tumors That Have Relapsed or Not Responded to Treatment

55 enrolled

Optic Nerve Glioma

NCT00002647 2013-09-20

Photodynamic Therapy With Porfimer Sodium in Treating Patients With Refractory Brain Tumors

Phase 1 Unknown

24 enrolled

CNSSarcoma

Familial ependymoma, Astrocytoma, Brain Neoplasms, Craniopharyngioma, Ependymoma, Glioblastoma, Medulloblastoma, Meningioma, Neoplasm Metastasis, Oligodendroglioma, Pinealoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Neoplasms, Neuroepithelial, Glioma, Subependymal, Gliosarcoma, Optic Nerve Glioma

NCT00360854 2013-09-20

Erlotinib Alone or in Combination With Radiation Therapy in Treating Young Patients With Refractory or Relapsed Malignant Brain Tumors or Newly Diagnosed Brain Stem Glioma

Phase 1 Unknown

48 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00003022 2013-07-03

Monoclonal Antibody Therapy in Treating Patients With Leptomeningeal Cancer

CNSDermatologicOther solid neoplasmSarcomaThoracic

Familial ependymoma, Uveal Melanoma, Astrocytoma, Brain Neoplasms, Ependymoma, Glioblastoma, Glioma, Lung Neoplasms, Medulloblastoma, Melanoma, Neuroblastoma, Oligodendroglioma, Retinoblastoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Neuroectodermal Tumors, Primitive, Gliosarcoma, Optic Nerve Glioma, Small Cell Lung Carcinoma

NCT00012181 2013-07-02

Flavopiridol in Treating Children With Relapsed or Refractory Solid Tumors or Lymphomas

CNSGenitourinaryLymphoidOther solid neoplasmSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Wilms Tumor, Neuroblastoma, Recurrence, Retinoblastoma, Osteosarcoma, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT00994500 2013-07-02

Vorinostat and Bortezomib in Treating Young Patients With Refractory or Recurrent Solid Tumors, Including Central Nervous System Tumors and Lymphoma

20 enrolled

CNSLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Meningioma, Oligodendroglioma, Recurrence, Lymphoma, Large B-Cell, Diffuse, Choroid Plexus Neoplasms, Lymphoma, Large-Cell, Anaplastic, Optic Nerve Glioma, Lymphoma, Extranodal NK-T-Cell, Dendritic Cell Sarcoma, Interdigitating

NCT00101270 2013-06-05

Oxaliplatin and Irinotecan in Treating Young Patients With Refractory Solid Tumors or Lymphomas

CNSDermatologicGastrointestinalGenitourinaryHead & NeckLymphoidSarcoma

24 enrolled

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Colonic Neoplasms, Medulloblastoma, Melanoma, Nasopharyngeal Neoplasms, Wilms Tumor, Neuroblastoma, Recurrence, Osteosarcoma, Lymphoma, Large B-Cell, Diffuse, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT01076530 2013-05-03

Vorinostat and Temozolomide in Treating Young Patients With Relapsed or Refractory Primary Brain Tumors or Spinal Cord Tumors

27 enrolled

CNSEndocrine

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Paraganglioma, Extra-Adrenal, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00003765 2013-02-05

O6-benzylguanine and Carmustine in Treating Children With Refractory CNS Tumors

36 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00053963 2013-01-16

FR901228 in Treating Children With Refractory or Recurrent Solid Tumors or Leukemia

CNSLymphoidOther hematologic neoplasm

Familial ependymoma, Astrocytoma, Blast Crisis, Medulloblastoma, Spinal Cord Neoplasms, Leukemia, Lymphocytic, Chronic, B-Cell, Choroid Plexus Neoplasms, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00363272 2013-01-16

Ispinesib in Treating Young Patients With Relapsed or Refractory Solid Tumors or Lymphoma

CNSLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Medulloblastoma, Spinal Cord Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT00004212 2012-05-16

DX-8951f in Treating Children With Advanced Solid Tumors or Lymphomas

CNSLymphoidSarcoma

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Lymphoma, Medulloblastoma, Oligodendroglioma, Recurrence, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma, Dendritic Cell Sarcoma, Interdigitating

NCT00030108 2012-03-15

Ixabepilone in Treating Young Patients With Solid Tumors or Leukemia That Haven't Responded to Therapy

CNSGastrointestinalGenitourinaryGynecologicLymphoidMyeloidOther hematologic neoplasmSarcoma

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Leukemia, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Eosinophilic, Acute, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma

NCT00036959 2012-03-15

ABT-751 in Treating Young Patients With Refractory Solid Tumors

90 enrolled

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Optic Nerve Glioma

NCT00303940 2012-03-15

Talabostat Combined With Temozolomide or Carboplatin in Treating Young Patients With Relapsed or Refractory Brain Tumors or Other Solid Tumors

26 enrolled

Familial ependymoma, Ovarian Germ Cell Cancer, Astrocytoma, Kidney Neoplasms, Liver Neoplasms, Medulloblastoma, Wilms Tumor, Neuroblastoma, Oligodendroglioma, Ovarian Neoplasms, Sarcoma, Osteosarcoma, Teratoma, Testicular Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Neuroectodermal Tumors, Primitive, Peripheral, Rhabdoid Tumor, Optic Nerve Glioma

NCT00503724 2012-03-06

Enzastaurin in Treating Young Patients With Refractory Primary CNS Tumors

32 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Neuroblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00572182 2012-03-06

MK0752 in Treating Young Patients With Recurrent or Refractory CNS Cancer

33 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00098761 2011-06-30

VNP40101M in Treating Young Patients With Recurrent, Progressive, or Refractory Primary Brain Tumors

42 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00112619 2011-06-30

Topotecan in Treating Young Patients With Neoplastic Meningitis Due to Leukemia, Lymphoma, or Solid Tumors

CNSLymphoidOther hematologic neoplasmSarcoma

19 enrolled

Familial ependymoma, Astrocytoma, Burkitt Lymphoma, Leukemia, Lymphoma, Medulloblastoma, Neoplasms, Unknown Primary, Oligodendroglioma, Recurrence, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Leukemia, Myelomonocytic, Juvenile, Dendritic Cell Sarcoma, Interdigitating, Meningeal Carcinomatosis

NCT00053118 2011-03-01

Chemotherapy and Stem Cell Transplantation in Treating Children With Central Nervous System Cancer

CNSLymphoidOther solid neoplasm

1 enrolled

Familial ependymoma, Astrocytoma, Lymphoma, Medulloblastoma, Neuroblastoma, Retinoblastoma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00006247 2009-10-14

SU5416 in Treating Children With Recurrent or Progressive Brain Tumors

33 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Optic Nerve Glioma

NCT00015899 2009-10-14

SCH 66336 in Treating Children With Recurrent or Progressive Brain Tumors

53 enrolled

Familial ependymoma, Astrocytoma, Medulloblastoma, Oligodendroglioma, Spinal Cord Neoplasms, Central Nervous System Neoplasms, Choroid Plexus Neoplasms, Rhabdoid Tumor, Optic Nerve Glioma

NCT00006246 2009-10-07

Busulfan in Treating Children and Adolescents With Refractory CNS Cancer