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Phase

Phase 2 17Phase NA 4Phase 3 3Phase 2/3 2Phase EARLY_PHASE1 1Phase 1 1

Status

Active not recruiting 1

Sponsor Class

NIH 1

Study Type

Interventional 1

Sponsor

Cancer Type

Head & Neck 1

Conditions

Squamous Cell Carcinoma of Head and Neck 14Head and Neck Neoplasms 11Glioblastoma 8Prostatic Neoplasms 7Carcinoma 6Rectal Neoplasms 5Pancreatic Neoplasms 5Gliosarcoma 5Carcinoma, Non-Small-Cell Lung 5Astrocytoma 5Neoplasm Metastasis 4Uterine Cervical Neoplasms 3Neoplasms 3Glioma 3Precursor Cell Lymphoblastic Leukemia-Lymphoma 2Oligodendroglioma 2Medulloblastoma 2Lymphoma, Follicular 2Lymphoma 2Liver Neoplasms 2Leukemia, Myeloid, Acute 2Laryngeal Neoplasms 2Hypopharyngeal Neoplasms 2Esophageal Neoplasms 2Central Nervous System Neoplasms 2Carcinoma, Hepatocellular 2Brain Neoplasms 2Wilms Tumor 1Waldenstrom Macroglobulinemia 1Unspecified Adult Solid Tumor, Protocol Specific 1

Interventions

pembrolizumab 7Magnetic Resonance Spectroscopy 5Cisplatin 5Specimen Handling 4Radiation 4Radiotherapy 3Biopsy 3motexafin gadolinium 2fludarabine 2Vorinostat 2Radiosurgery 2Fluorouracil 2Cyclophosphamide 2zimberelimab 1peposertib 1ipatasertib 1fludarabine phosphate 1dl1520 1Surgical Procedures, Operative 1Radiotherapy, Intensity-Modulated 1Proton Therapy 1Platinum 1Paclitaxel 1Nivolumab 1Lidocaine 1L 778,123 1Immunohistochemistry 1Hyperthermia, Induced 1Gemcitabine 1Fluorodeoxyglucose F18 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

1 trials
RecentStart dateEnrollment
Phase 1 × Oropharyngeal Neoplasms × Radiotherapy, Intensity-Modulated × Clear all
NCT04533750 2026-04-13

Testing the Addition of M3814 (Peposertib) to Radiation Therapy for Patients With Advanced Head and Neck Cancer Who Cannot Take Cisplatin

National Cancer Institute (NCI)

Phase 1 Active not recruiting
21 enrolled
Head & Neck

Carcinoma, Hypopharyngeal Neoplasms, Laryngeal Neoplasms, Mouth Neoplasms, Oropharyngeal Neoplasms

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