Announcements Trials
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Phase

Phase 2 42Phase 1 34Phase 1/2 17Phase NA 11Phase EARLY_PHASE1 3Phase 3 2Phase 2/3 1

Status

Recruiting 2Active not recruiting 1

Sponsor Class

OTHER 2INDUSTRY 1

Study Type

Interventional 3

Sponsor

Cancer Type

Sarcoma 3Genitourinary 2CNS 2Thoracic 1Lymphoid 1Head & Neck 1Gastrointestinal 1Dermatologic 1Breast 1

Conditions

Breast Neoplasms 39Glioblastoma 37Glioma 34Prostatic Neoplasms 32Neoplasms 28Multiple Myeloma 26Pancreatic Neoplasms 24Brain Neoplasms 23Colorectal Neoplasms 19Recurrence 18Squamous Cell Carcinoma of Head and Neck 16Melanoma 16Lymphoma 15Lung Neoplasms 15Neoplasm Metastasis 14Sarcoma 13Lymphoma, B-Cell 13Carcinoma, Non-Small-Cell Lung 13Triple Negative Breast Neoplasms 12Leukemia, Myeloid, Acute 12Hematologic Neoplasms 12Head and Neck Neoplasms 12Advanced Solid Tumors 10Stomach Neoplasms 9Ovarian Neoplasms 9Skin Neoplasms 8Precursor Cell Lymphoblastic Leukemia-Lymphoma 8Neuroblastoma 8Lymphoma, Non-Hodgkin 8Colonic Neoplasms 8

Interventions

glucarpidase 1gamma-Glutamyl Hydrolase 1

Date Range

30 days90 days1 yearAll

Options

Has results Has announcements

Clinical Trials

3 trials
RecentStart dateEnrollment
Phase EARLY_PHASE1 × Osteosarcoma × 1 year × Clear all
NCT07628634 2026-06-05

Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors

University of California, Irvine

Phase EARLY_PHASE1 Recruiting
25 enrolled
CNSDermatologicGenitourinaryLymphoidSarcoma

Adenocarcinoma, Carcinoma, Basal Cell, Carcinoma, Squamous Cell, Carcinoma, Transitional Cell, Endocrine Gland Neoplasms, Glioma, Leiomyosarcoma, Lymphoma, Melanoma, Neoplasms, Germ Cell and Embryonal, Rhabdomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Carcinoma, Ductal

NCT03960177 2026-01-07

Glucarpidase After High-Dose Methotrexate in Patients With Osteosarcoma

OHSU Knight Cancer Institute

Phase EARLY_PHASE1 Active not recruiting
12 enrolled
Sarcoma

Osteosarcoma

NCT06645808 2025-12-29

VARTUTRACE

Var2 Pharmaceuticals

Phase EARLY_PHASE1 Recruiting
32 enrolled
BreastCNSGastrointestinalGenitourinaryHead & NeckSarcomaThoracic

Squamous Cell Carcinoma of Head and Neck, Urinary Bladder Neoplasms, Breast Neoplasms, Chondrosarcoma, Colonic Neoplasms, Esophageal Neoplasms, Glioblastoma, Lung Neoplasms, Neoplasms, Pancreatic Neoplasms, Rectal Neoplasms, Sarcoma, Osteosarcoma, Stomach Neoplasms

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