Clinical Trials Browser

Osteosarcoma × Methotrexate × Clear all

NCT05691478 2026-05-27

A Study to Test the Addition of the Drug Cabozantinib to Chemotherapy in Patients With Newly Diagnosed Osteosarcoma

Phase 2/3 Recruiting

Osteosarcoma

NCT07321912 2026-05-26

Eflornithine (DFMO) for Ewing Sarcoma and Osteosarcoma

Phase 2 Recruiting

Sarcoma, Ewing, Osteosarcoma

NCT07560826 2026-05-01

The CATSINDO Trial - Clinical and Translational Study in Newly Diagnosed Osteosarcoma

Phase 2 Not yet recruiting

Osteosarcoma

NCT07477457 2026-03-17

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

Phase 2 Recruiting

Neoplasm Metastasis, Osteosarcoma

NCT00470223 2025-06-08

OS2006

Phase 3 Active not recruiting

Sarcoma, Osteosarcoma

NCT02517918 2025-06-08

METZOLIMOS

Phase 1 Completed

23 enrolled 15 charts

Osteosarcoma

NCT03277924 2024-08-13

ImmunoSarc

Phase 1/2 Completed

Chondrosarcoma, Extraskeletal Myxoid, Bone Neoplasms, Chondrosarcoma, Hemangioendothelioma, Hemangiosarcoma, Leiomyosarcoma, Sarcoma, Sarcoma, Ewing, Osteosarcoma, Sarcoma, Synovial, Sarcoma, Clear Cell, Sarcoma, Alveolar Soft Part, Hemangioendothelioma, Epithelioid, Histiocytoma, Malignant Fibrous, Solitary Fibrous Tumors

NCT01459484 2024-05-20

ISG/OS-2

Phase 2 Completed

Osteosarcoma

NCT05899751 2024-05-10

Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate

GenitourinaryOther hematologic neoplasmSarcoma

Osteosarcoma, Water Intoxication, Hematologic Neoplasms, Acute Kidney Injury, Drug-Related Side Effects and Adverse Reactions

NCT05057130 2024-04-01

Neoadjuvant Combination of Doxorubicin, Cisplatin and Methotrexate in Patients Aged 24-40 Years With Primary Bone Tumors

Phase 2/3 Unknown

Bone Neoplasms, Neoplasms, Connective Tissue, Sarcoma, Osteosarcoma, Neoplasms, Connective and Soft Tissue

NCT00667342 2023-08-07

A Study of Bevacizumab in Combination With Chemotherapy for Treatment of Osteosarcoma

Phase 2 Completed

43 enrolled 25 charts

Osteosarcoma, Histiocytoma, Malignant Fibrous

NCT00134030 2023-06-07

EURAMOS-1

Phase 3 Completed

1,334 enrolled 17 charts

Osteosarcoma

NCT00634504 2022-06-06

LVPK

Phase 1 Completed

20 enrolled 9 charts

LymphoidOther hematologic neoplasmSarcoma

Leukemia, Lymphoma, Osteosarcoma, Renal Insufficiency

NCT01176981 2021-10-28

Outpatient Administration of High Dose Methotrexate (HD MTX) in Patients With Osteosarcoma

Phase 3 Completed

6 enrolled 2 charts

Osteosarcoma

NCT01848457 2020-03-16

Preventing Nephrotoxicity and Ototoxicity From Osteosarcoma Therapy

Phase 2 Completed

13 enrolled 15 charts

Ototoxicity, Neoplasms, Osteosarcoma

NCT03360760 2018-08-28

Timing of Surgery in Nonmetastatic Osteosarcoma of the Pelvis and Sacrum

Phase NA Unknown

Osteosarcoma

NCT03063983 2017-03-13

GLATO2017

Phase 2 Unknown

Neoplasm Metastasis, Osteosarcoma

NCT02383901 2016-09-05

FORTO

Osteosarcoma

NCT00586846 2016-01-20

Phase II Study of Chemotherapy and Pamidronate for the Treatment of Newly Diagnosed Osteosarcoma

Phase 2 Completed

40 enrolled 6 charts

Osteosarcoma

NCT01758666 2015-12-22

A Clinical Research on the Relation of Blood Drug Concentration and Calcium Folinate Rescued in High-dose MTX Therapy

Phase NA Unknown

Osteosarcoma

NCT00019864 2015-06-08

Combination Chemotherapy Before and After Surgery in Treating Patients With Osteosarcoma

Phase 2 Terminated

Sarcoma, Osteosarcoma, Cardiotoxicity

NCT02022358 2015-06-04

Will Glucarpidase After Methotrexate Treatment for Bone Sarcoma Lead to Fewer Side Effects and Reduce Chemotherapy Delays?

Phase 2 Terminated

Osteosarcoma, Mucositis

NCT00673179 2014-09-10

Doxorubicin With Cisplatin, High-Dose Methotrexate, and Additional Risk-Adapted Outpatient Chemotherapy

Phase NA Terminated

7 enrolled 3 charts

Osteosarcoma

NCT00742924 2014-07-04

Zoledronic Acid and Combination Chemotherapy in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

Phase 1 Completed

24 enrolled 9 charts

Sarcoma, Osteosarcoma

NCT00513981 2013-06-26

High-Dose Methotrexate in Treating Young Patients With Solid Tumors

Phase 1 Completed

Familial ependymoma, Sarcoma, Osteosarcoma, Central Nervous System Neoplasms

NCT00003776 2013-06-21

Combination Chemotherapy and Surgery in Treating Patients With Newly Diagnosed Metastatic Osteosarcoma

Phase 2 Completed

Sarcoma, Osteosarcoma

NCT00023998 2013-02-04

Chemotherapy With or Without Trastuzumab in Treating Patients With Metastatic Osteosarcoma

Phase 2 Completed

Osteosarcoma

NCT00119301 2013-01-17

Methotrexate, Trimetrexate Glucuronate, and Leucovorin in Treating Patients With Refractory or Recurrent Osteosarcoma

Phase 1 Completed

Sarcoma, Osteosarcoma

NCT00180908 2005-09-16

Comparison of High-Dose Methotrexate (HDM) Plus Doxorubicin to HDM Plus Etoposide-Ifosfamide in Osteosarcoma Children

Phase 3 Completed

Osteosarcoma